… progression, we comprehensively analyzed the relationship between all m6A methylation
regulators and osteosarcoma … to be the first mRNA of m6A demethylase [37]. As an “eraser” of …

… To explore the underlying mechanism involved in m6A modification–mediated OS progression,
we performed a systematic bioinformatic analysis based on an OS genome meta-cohort. …

… , the prognosis of patients with osteosarcoma (OS) remains poor, … that the m 6 A demethylase
FTO could be a candidate … of DACT1 via m 6 A demethylation, which decreased DACT1 …

… The m 6 A regulators are also linked with the progression and prognosis of OS. Overexpression
of the m 6 A demethylase ALKBH5 notably restrains the growth, migration, and invasion …

… by two mammalian RNA demethylases, alkylation repair … balance of m6A methylation and
demethylation in mammalian cells. … in the progress of human osteosarcoma remain unknown. …

… are critical for tumor initiation, promotion, and progression in OS. This paper reviews the …
Fat mass and obesity-associated protein (FTO) were the first m6A demethylase to be discovered …

… FTO was the first identified m 6 A demethylase (36). Since then, research on m 6 A modification
… Silencing ELAVL1 inhibits osteosarcoma progression by decreasing the expression of …

… The dynamic and reversible regulation of m6A modification is regulated by methylases (writers),
demethylases (erasers), and m 6 A binding proteins (readers). Representative genes …

… The effect of m6A modification on RNA depends mainly on the dynamic regulation of … and
demethylases [12]. It has been shown that the m6A level is high in osteosarcoma tissues and …

… Clinical data unveiled that osteosarcoma patients with higher FOXD2-AS1 … the osteosarcoma
progression through m 6 A manner, which may provide new concepts for osteosarcoma …