The cytokine storm and factors determining the sequence and severity of organ dysfunction in multiple organ dysfunction syndrome

H Wang, S Ma - The American journal of emergency medicine, 2008 - Elsevier
organ dysfunction were discussed in depth. In the early phase of MODS, circulating cytokines
cause universal endothelium injury in organs… space of various organs is considered a main

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… (ARDS) or multiple organ failure. It has been reported that a cytokine storm is associated with
… It is considered to be the main cause of disease severity and death in patients with COVID-…

[PDF][PDF] Cytokines storm of COVID-19 and multi systemic organ failure: A review

ZNM Albarzanji, TA Mahmood, ER Sarhat… - Sys Rev Pharm, 2020 - academia.edu
… It is uncertain which of these mechanisms plays a main role in the diffusion of COVID-19.
Much of the airborne illnessinvestigation prior to the present pandemic focused on "violent" …

The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
… and organs. … Cytokine storm syndrome (CSS) has generally been described as a collection
of clinical manifestations resulting from an overactivated immune system. Cytokine storms (…

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
… of cytokine storm has been reported to be one of the main causes … Similarly, cytokine storm
is also a common feature of severe … severity of organ dysfunction in multiple organ dysfunction …

Clinical features of cytokine storm syndrome

M Shimizu - Cytokine storm syndrome, 2019 - Springer
cytokines, causing a cytokine storm. Many clinical features of CSS can be explained by the
effects of proinflammatory cytokinescytokines can disrupt homeostasis of many organ systems…

Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… thrombi and even multiple organ damage. Release of NETs has also been reported by cytokines
(eg, IL-… cytokines leads to cytokine storm with the known potentially lethal courses [168]. …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
cytokine storm pathophysiology mechanisms and discusses how it can lead to dysfunction
and failure in each organ … TNF-α, IL-6, and IFN-γ, which are the main inflammatory cytokines

Cytokine storm and sepsis-induced multiple organ dysfunction syndrome

JA Carcillo, B Shakoory - Cytokine Storm Syndrome, 2019 - Springer
cytokine storm known as MARS or mixed anti-inflammatory response syndrome. This
cytokine storm… dissonance, is characterized by high circulating IL-6 and IL-10 levels, and …

An enlightening role for cytokine storm in coronavirus infection

Z Zhao, Y Wei, C Tao - Clinical Immunology, 2021 - Elsevier
… regarding the physiology of cytokine storm in the context of … among the cytokine storm,
immune response and organ functions. … , and being main executors of the cytokine storm [17,18]. …