Made by cells for cells–extracellular vesicles as next-generation mainstream medicines

TH Phan, SY Kim, C Rudge… - Journal of Cell …, 2022 - journals.biologists.com
medicine has only taken us so far in reducing disease and tissue damage. Extracellular
vesicles … , have been hailed as a next-generation medicine. EVs deliver various biomolecules, …

[HTML][HTML] Can stem cells beat COVID-19: advancing stem cells and extracellular vesicles toward mainstream medicine for lung injuries associated with SARS-CoV-2 …

W Chrzanowski, SY Kim, L McClements - Frontiers in Bioengineering …, 2020 - frontiersin.org
A number of medicines are currently under investigation for … and, more recently, their secreted
extracellular vesicles (EVs), are … therapies towards mainstream treatment for COVID-19. …

Alternative methods for characterization of extracellular vesicles

F Momen-Heravi, L Balaj, S Alian, J Tigges… - Frontiers in …, 2012 - frontiersin.org
… In this mini-review we discuss some new mainstream technologies including flow cytometry,
scattering and fluorescence flow cytometry, impedance-based flow cytometry, transmission …

Diagnostic and therapeutic potential of extracellular vesicles

SP Kodam, M Ullah - Technology in Cancer Research & …, 2021 - journals.sagepub.com
Extracellular vesicles (EVs) are naturally phospholipid enclosed nanovesicles released by
many cells in the body. They are stable in circulation, have low immunogenicity, and act as …

Good things come in small packages: Overcoming challenges to harness extracellular vesicles for therapeutic delivery

D Ingato, JU Lee, SJ Sim, YJ Kwon - Journal of controlled release, 2016 - Elsevier
… This review summarizes current research in therapeutic delivery via extracellular vesicles
and thoroughly examines methods for overcoming challenges associated with EVs in …

Emerging technologies in extracellular vesicle-based molecular diagnostics

S Jia, D Zocco, ML Samuels, MF Chou… - Expert review of …, 2014 - Taylor & Francis
… environment of personalized medical therapies and biomarker… Here we report on the use of
extracellular vesicles (EVs) as a … assay technologies into mainstream clinical diagnostics and …

Engineered extracellular vesicles and their mimics in cardiovascular diseases

J Lai, C Huang, Y Guo, L Rao - Journal of Controlled Release, 2022 - Elsevier
Extracellular vesicles (EVs), which are lipid vesicles secreted by cells, play key roles in …
superior properties can overcome limitations of traditional medicine, thus emerging as alternative …

Putting value on extracellular vesicles: practical economies of biomedical research and development

I Helén, H Tarkkala - Science & …, 2022 - sciencetechnologystudies.journal.fi
… the mainstream view emphasising the dominance of commercial value. … extracellular vesicles
(EVs). The consortium was part of a research programme on personalised medicine (GiD) …

[图书][B] Extracellular Vesicles: Applications to Regenerative Medicine, Therapeutics and Diagnostics

W Chrzanowski, CT Lim, SY Kim - 2021 - books.google.com
Extracellular vesicles (EVs) are membrane-enclosed … in regenerative medicine for the treatment
of major medical conditions… We believe that EVs will soon become mainstream medicine. …

Mass spectrometry of extracellular vesicles

G Pocsfalvi, C Stanly, A Vilasi, I Fiume… - Mass spectrometry …, 2016 - Wiley Online Library
… These vesicles are in the center of interest in biology and medical sciences, and form a very
… The current mainstream proteomics workflow is based on proteolytic (tryptic) digestion of the …