A systematic review of candidate genes for major depression

A Norkeviciene, R Gocentiene, A Sestokaite… - Medicina, 2022 - mdpi.com
candidate genes were examined in genetic association studies and their association with
major depressive … of keywords: “major depressive disorder” OR “major depression” AND “…

No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple large samples

R Border, EC Johnson, LM Evans… - American Journal of …, 2019 - Am Psychiatric Assoc
… studies per candidate gene a a Panel A shows cumulative sums of the estimated number
of depression candidate gene studies identified by our algorithm per year per gene from 1991 …

Poor replication of candidate genes for major depressive disorder using genome-wide association data

FJ Bosker, CA Hartman, IM Nolte, BP Prins… - Molecular …, 2011 - nature.com
… To prevent any bias from the results of the GAIN MDD study, we identified candidate genes
for MDD before the results from the GAIN MDD study became available. Therefore, a so-…

A comprehensive network and pathway analysis of candidate genes in major depressive disorder

P Jia, CF Kao, PH Kuo, Z Zhao - BMC systems biology, 2011 - Springer
… properties of depression genes We collected 151 major depressive disorder candidate genes
(… 6) for the schizophrenia candidate genes (131 of the 160 genes mapped onto the human …

Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses

H Hori, D Sasayama, T Teraishi, N Yamamoto… - Scientific reports, 2016 - nature.com
… molecules for depression were included. The co-expression network of candidate genes
was … and confirmed that the candidate genes are worthwhile targets for depression research. …

… refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive …

X Luo, N Stavrakakis, BW Penninx… - American Journal of …, 2016 - Wiley Online Library
… 245 polymorphisms in 97 candidate genes, from which we were able to investigate 185
SNPs in 89 genes. We replicated nine candidate SNPs in eight genes for MDD and six in five …

TOMM40 rs2075650 may represent a new candidate gene for vulnerability to major depressive disorder

M McFarquhar, R Elliott, S McKie, E Thomas… - …, 2014 - nature.com
… Despite TOMM40 rs2075650 being a good candidate for major depressive disorder (MDD),
its possible effect on depression-related phenotypes has not yet been investigated. …

The kynurenine pathway in major depression: haplotype analysis of three related functional candidate genes

S Claes, AM Myint, K Domschke, J Del-Favero… - Psychiatry …, 2011 - Elsevier
… of three candidate genes of the three enzymes involved in this metabolism. The three genes,
… 338 (266 major depression and 72 bipolar depression) unrelated Caucasian patients with …

The genetics of major depression

J Flint, KS Kendler - Neuron, 2014 - cell.com
… literature on candidate gene studies, which we review next. In addition, GWAS findings
inform us about the extent to which rare but more highly penetrant genetic variants might …

High-coverage whole-exome sequencing identifies candidate genes for suicide in victims with major depressive disorder

D Tombácz, Z Maróti, T Kalmár, Z Csabai, Z Balázs… - Scientific reports, 2017 - nature.com
… This report also identified several candidate genes that have not been associated with any
diseases until now. Additionally, our study also revealed that the TGF-β signalling pathway …