COVID19 pandemic: mechanism, diagnosis, and treatment

V Kumar, KU Doshi, WH Khan… - Journal of chemical …, 2021 - Wiley Online Library
… Home Rapid Antibody tests for COVID-19 are being developed … to COVID-19, although they
do not always indicate COVID-19. … Major COVID-19 vaccine development programs under …

COVID-19 outbreak: history, mechanism, transmission, structural studies and therapeutics

D Yesudhas, A Srivastava, MM Gromiha - Infection, 2021 - Springer
… The coronavirus outbreak emerged as a severe pandemic, claiming more than 0.8 million …
raised a major global health concern. We survey the history and mechanism of coronaviruses, …

Cytokine release syndrome in COVID-19: a major mechanism of morbidity and mortality

Y Que, C Hu, K Wan, P Hu, R Wang, J Luo… - International reviews …, 2022 - Taylor & Francis
coronavirus 2 (SARS-CoV-2) erupted in Hubei Province of China in December 2019 and has
become a pandemic. Severe COVID-19 … The molecular mechanisms for CRS in COVID-19

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
… syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the biological
mechanisms underlying COVID-19, alternative or novel therapeutic targets for COVID-19

Interfering with interferons: A critical mechanism for critical COVID-19 pneumonia

HC Su, H Jing, Y Zhang… - Annual Review of …, 2023 - annualreviews.org
… In this review, we have focused on the mechanisms of life-threatening COVID-19 pneumonia
in humans. We now know that inborn errors of TLR3- or TLR7-dependent type I interferon …

[HTML][HTML] COVID19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches

AV Sorokin, SK Karathanasis, ZH Yang… - The FASEB …, 2020 - ncbi.nlm.nih.gov
… through an IL‐6–dependent mechanism that increases endothelial cell permeability to
oxLDL; 62 IL‐6 is a major cytokine released during the COVID19 cytokine storm. In humans, …

[PDF][PDF] Mechanism of antiviral immune response and COVID-19 infection

S Sheshe, A Nazifi, AM Labbo, GM Khalid… - Asian Journal of …, 2020 - academia.edu
… The immune system is the major protective system of the body … the skin responsible for the
major protection of the body [4]. … of immunity and involves key mechanisms for activation of …

The mechanism of multiple organ dysfunction syndrome in patients with COVID19

W Zhao, H Li, J Li, B Xu, J Xu - Journal of medical virology, 2022 - Wiley Online Library
… Moreover, previous that described the pathology and the molecular changes in patients
with COVID-19 suggested that immunosenescence is also a major driver of high mortality in …

Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
COVID-19 patients, in order to achieve a major clinical response or partial respond defined
by WHO in a time-frame of two weeks ( Table 4 ). This trial is including hospitalized patients …

Mechanism of inflammatory response in associated comorbidities in COVID-19

TMC de Lucena, AF da Silva Santos… - Diabetes & Metabolic …, 2020 - Elsevier
… Diabetes mellitus (DM) is a major risk factor for severity and mortality in individuals infected
… hyperglycemia may be important in COVID-19 pathogenesis. Possible changes in ACE2 …