… Malaria parasites undergo a sporogonic cycle in the mosquito vector. Sporozoites, the form
… The circumsporozoite protein (CS), one of the major proteins synthesized by salivary gland …

… Plasmodium falciparum sporozoites invade liver cells in humans and set the stage for
malaria infection. Circumsporozoite protein (CSP), a predominant surface antigen on sporozoite …

… Our results indicate that by the id route, ΔNfull sporozoites have a very low capacity to
initiate malaria infection possibly because these sporozoites cannot exit the dermis. To test this, …

… malaria parasites, Plazmodium falciparum and Plazmodium vivax. The antibodies reacted
with polypeptides (circumsporozoite proteins) … and by the circumsporozoite precipitin reaction. …

… The Plasmodium falciparum circumsporozoite protein (CSP) is critical for sporozoite
function and invasion of hepatocytes. Given its critical nature, a phase III human CSP malaria …

… A safe and effective vaccine will likely be necessary for the control or eradication of malaria
… on the Plasmodium falciparum circumsporozoite protein (PfCSP) of the malaria parasite. …

… the liver where they initiate the first stage of malaria infection. All species of malaria sporozoites
are uniformly covered by the circumsporozoite protein (CS), which contains a conserved …

… The sequences of the genes encoding the circumsporozoite proteins ofP. vivax isolates
VK247 and VK210 bounded by regionI and region II. Oligonudeotide primers homologous to …

… Here, we show that circumsporozoite protein (CSP) is required for rodent malaria oocysts to
… In this work, we find that a mutation of the circumsporozoite protein (CSP) pexel I/II domain …

… This possibility is consistent with the observation that CS protein binding to hepatocytes,
cells invaded by sporozoites during the primary stage of malaria infection, was inhibited by …