… The development and deployment of an effective malaria vaccine is considered a further
important step towards reducing the disease burden. RTS,S/AS01 is a malaria vaccine …

Background The efficacy and safety of the RTS,S/AS01 candidate malaria vaccine during 18
months of follow-up have been published previously. Herein, we report the final results from …

… African countries. This study seeks to identify whether vaccination could reach additional
children … malaria cases, in malaria-endemic African countries, in light of the coverage of EPI …

… • It is expected there will be high demand for a malaria vaccine. However, supply will be the
… malaria vaccines are being developed specifically for use in children in subSaharan Africa, …

… all three doses of vaccine according to protocol. After 250 children had an episode of
severe malaria, we evaluated vaccine efficacy against severe malaria in both age categories. …

… especially among children and pregnant women in Africa. An effective malaria vaccine would
… burden and could contribute to elimination of malaria in some regions of the world. Current …

… of clinical malaria among 223 children randomly assigned to the RTS,S/AS01 group and
992 episodes among 224 children randomly assigned to the control group. The vaccine efficacy…

… malaria transmission settings in sub-Saharan Africa demonstrated that the RTS,S/AS01 vaccine
can reduce clinical and severe malaria … as a 3- or 4-dose regimen in children [7], [8], [9], […

… malaria vaccine will reduce the number of hospital admission for malaria illness among
children … with PATH's Malaria vaccine initiative and a network of African research centers. …

… RTS,S/AS01 malaria vaccine, done in 11 centres in sub-Saharan Africa, showed moderate
… incidence of severe malaria was delayed in RTS,S/AS01 vaccinated children. These findings …