Designing a malaria vaccine.

GA Targett - Journal of clinical pathology, 1997 - ncbi.nlm.nih.gov
… peptide SPf 66, the one P falciparum candidate vaccine to have … The vaccine gave 30-35%
protection against clinical malaria … in1-5 year old children in Tanzania where transmission is …

Naturally acquired cellular immune responses to the synthetic malarial peptide SPf66 in children in Papua New Guinea

F Al-Yaman, B Genton, J Taraika… - Transactions of the …, 1997 - academic.oup.com
… Vaccination of Tanzanian children with SPf66 resulted in reduction in the number of multiple
… with multiple infections appeared to be eliminated by vaccination (BECK et al., 1997). …

[HTML][HTML] A brief history of selected malaria vaccine and medical interventions pursued by the Swiss Tropical and Public Health Institute and partners, 1943-2021

L Meier, G Casagrande, S Abdulla, H Masanja - Acta Tropica, 2022 - Elsevier
… (from Patarroyo's team) tests of SPf66 to be conducted in other … The Idete trial including 586
children aged 1-5 years was the … “It wasn't about travelling to Tanzania to collect a few blood …

Malaria vaccine trials

B Greenwood, P Alonso - Malaria Immunology, 2002 - karger.com
… falciparum infections in Tanzanian children during the phase III trial of the malaria … falciparum
genotypes in Gambian children immunized with the malaria vaccine SPf66. Trans R Soc …

Malaria Vaccine Raises a Dilemma: Colombian scientist Manuel Patarroyo has developed possibly the first effective malaria vaccine and wants the world's 300 million …

J Maurice - Science, 1995 - science.org
Tanzania with 600 young children and conducted independently of Patarroyo. Because it
was the first field trial to pit the vaccine against malaria … distribute his SPf66 malaria vaccine to …

Malaria vaccines

SL Hoffman, JE Epstein - Essential Malariology, 4Ed, 2017 - taylorfrancis.com
… for older children who would die of cerebral malaria (see Chapter 8). The epidemiology
of … An efficacy trial of the malaria vaccine SPf66 in Gambian infants - second year of follow-up. …

Safety evaluation of SPf66 malaria vaccine in Brazil

LM Urdaneta, A Prata, CJ Struchiner… - Revista da Sociedade …, 1996 - SciELO Brasil
… of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania.
… schedule for field trials with the synthetic malaria vaccine SPf66. Parasite Immunology 14:95…

Synthetic malaria vaccine, SPf66

VS Chauhan - Current Science, 1995 - JSTOR
… ,32, found SPf66 to be a poor the child was … of SPf66 in the Kilombero though its reported
efficacy is much lower 10 District of Tanzania, an area under malaria than most other vaccines

Field trials of an asexual blood stage malaria vaccine: studies of the synthetic peptide polymer SPf66 in Thailand and the analytic plan for a phase IIb efficacy study

WR Ballou, J Blood, T Chongsuphajaissidhi… - Parasitology, 1995 - cambridge.org
… antibody responses to SPf66 in a random subsample of approximately 100 children. The …
chemically synthesized subunit malaria vaccine, is safe and immunogenic in Tanzanians

Malaria vaccines: past, present and future

L Von Seidlein, P Bejon - Archives of disease in childhood, 2013 - adc.bmj.com
… candidate attracted more attention than SPf66, … Tanzanian children showed a vaccine
protective efficacy at 8 -month follow-up of 56% (99% CI 31% to 72%, p<0.001) against all malaria