… Given the complexity and wide range of malaria vaccines … ‐stage vaccines (the subject of this
review); SPf66 vaccine; … children should be pretreated for malaria before vaccination, half of …

… In a randomized trial of SPf66 vaccine P. falciparum malaria in children in southern Tanzania,
the best estimate of the SPf66 vaccine protective efficacy was 31% (95% CI: 0.52) (Alonzo …

… malaria vaccine, the Spf66 fusion protein of the CSP and a blood stage malaria antigen was
trialled as a vaccine, the … in high levels in children protected from clinical malaria, further the …

… We randomly assigned 701 children living in Ifakara, southern Tanzania, sulphadoxine-…
of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania. …

… -exposed populations (eg SPf66 [18], Combination B [19], RTS,S [20,21], ME-TRAP-based …
Malaria Infections (CHMIs) and in adult, child and infant populations exposed to natural …

… For these reasons we defined malaria as a febrile episode, … malaria vaccine in a given
eco-epidemiological situation? To what extent will the results of SPf66's trials in Gambia, Tanzania…

… The majority of malaria related mortality is in young children residing in sub-Saharan
Africa. … study of the malaria vaccine SPf66 in Gambian infants. Parasite Immunol. 17, 441-444. …

… we expect many more African children to be protected from malaria and grow into healthy
adults.” … In 1988, asexual stage vaccine (SPf66 candidate), emerged in Colombia and had an …

… of looking after our children seemed overwhelming and her … Description of SPf66; The
search for a vaccine against malaria … infection because the estimated efficacy in the Tanzanian …

… in Tanzania, researchers have established that SPf66 can be given safely to children living
in an area of intense perennial malarial … study of 50 such children, anti-SPf66 antibody titres …