… The SPf66 vaccine consists of a 45 amino-acid peptide, … in a South American and a Tanzanian
study, but failed to show … African children has changed the landscape of malaria vaccine …

… to receive three doses of either RTS,S/AS02A candidate malaria vaccine or a control vaccine
… of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania. …

… children in areas of high malaria risk. Foetal haemoglobin was associated with delayed first
episode of febrile malaria … In a study conducted in Tanzania by Lusingu and colleagues, total …

… the immune response to malaria, index cases of severe malaria in children aged 3 months
to 14 years … A trial of the synthetic malaria vaccine SPf66 in Tanzania: rationale and design …

… is that the boosting provided by a malaria vaccine may be more efficient in the presence of
… by a malaria vaccine was also found for IgG3 responses in Tanzanian children after SPf66 …

… intensity dependent and SPf66 vaccination was thus stopped … carried out involving 45
children between 12 and 24 months … on 16 Swiss and 40 Tanzanian volunteers who were given …

… In the past decade, SPf66, a synthetic polypeptide malaria vaccine has been tested in
various … the association of SPf66 with 30% protection against malaria in some populations …

… Thus, for instance, in the first major Tanzanian trial of the SPf66 vaccine [ … No difference
was detected in the distribution of these variants between SPf66-vaccinated children and the …

… Within a small cohort of children in an area of high transmission in Tanzania, we described
intra-individual consistency, over several years, in the number of infecting P. falciparum …

… –5 y old children in Tanzania concluded that SPf66 was safe, immunogenic and reduced the
risk of clinical malaria by ~30%.Citation 51 Partial vaccine efficacy reportedly extended well …