… or comparator vaccine. VE against clinical malaria in children during the 18 mo after vaccine … VE during the 20 mo after vaccine dose 1 (intention to treat [ITT]) was 45% (95% CI 41% to …
Y Guerra Mendoza, E Garric, A Leach… - Human vaccines & …, 2019 - Taylor & Francis
… of our study sites, children participating in this trial had a 70% … provided in context of the trial. The childhood deaths that … phase III trials has also been observed for other vaccines; no …
… malariavaccine during 18 months of follow-up have been published previously. Herein, we report the final results from the same trial, … of severe malaria in the C3C group, 116 children …
U D'alessandro, A Leach, BO Olaleye, GW Fegan… - The lancet, 1995 - thelancet.com
… efficacy in an area of intensive malaria transmission in Tanzanian children, 1-5 years old. … -controlled trial of SPf66 against clinical P falciparum malaria in Gambian infants. 630 children, …
RTS, S Clinical Trials Partnership - New England Journal of …, 2011 - Mass Medical Soc
… all three doses of vaccine according to protocol. After 250 children had an episode of severe malaria, we evaluated vaccine efficacy against severe malaria in both age categories. …
SB Sirima, B Mordmüller, P Milligan, UA Ngoa… - Vaccine, 2016 - Elsevier
… malariavaccine to be evaluated in a large multicenter trial. GMZ2 was well tolerated and immunogenic, and reduced the incidence of malaria… for the vaccine to have a public health role. …
… We conducted a double-blind, randomized trial of RTS,S/AS01E vaccine as compared with … children to receive either the candidate malariavaccine or a licensed rabies vaccine in a 1:1 …
A Olotu, G Fegan, J Wambua… - … England Journal of …, 2016 - Mass Medical Soc
… In an analysis that was not prespecified, we used data from 870 children who were under active surveillance in the same trial area to determine exposure indexes and categorized the …
… -infected children on ART [13]. Here, we report results of RTS,S/AS01 vaccination in a small subset of children … controlled efficacy trial which enrolled more than 15,000 children in seven …