Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand

F Nosten, C Luxemburger, DE Kyle, WR Ballou… - The lancet, 1996 - thelancet.com
trials of SPf66 malaria vaccinetrial of the SPf66 vaccine conducted in Karen children aged
2–15 living in a malarious region of northwestern Thailand. Recombinant hepatitis B vaccine

Efficacy and safety of the RTS, S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 …

RTS, S Clinical Trials Partnership (2014) - PLoS medicine, 2014 - journals.plos.org
… or comparator vaccine. VE against clinical malaria in children during the 18 mo after vaccine
… VE during the 20 mo after vaccine dose 1 (intention to treat [ITT]) was 45% (95% CI 41% to …

Safety profile of the RTS, S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa

Y Guerra Mendoza, E Garric, A Leach… - Human vaccines & …, 2019 - Taylor & Francis
… of our study sites, children participating in this trial had a 70% … provided in context of the
trial. The childhood deaths that … phase III trials has also been observed for other vaccines; no …

… safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

S Rts - Lancet, 2015 - thelancet.com
malaria vaccine during 18 months of follow-up have been published previously. Herein, we
report the final results from the same trial, … of severe malaria in the C3C group, 116 children

Efficacy trial of malaria vaccine SPf66 in Gambian infants

U D'alessandro, A Leach, BO Olaleye, GW Fegan… - The lancet, 1995 - thelancet.com
… efficacy in an area of intensive malaria transmission in Tanzanian children, 1-5 years old. …
-controlled trial of SPf66 against clinical P falciparum malaria in Gambian infants. 630 children, …

[HTML][HTML] First results of phase 3 trial of RTS, S/AS01 malaria vaccine in African children

RTS, S Clinical Trials Partnership - New England Journal of …, 2011 - Mass Medical Soc
… all three doses of vaccine according to protocol. After 250 children had an episode of
severe malaria, we evaluated vaccine efficacy against severe malaria in both age categories. …

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

SB Sirima, B Mordmüller, P Milligan, UA Ngoa… - Vaccine, 2016 - Elsevier
malaria vaccine to be evaluated in a large multicenter trial. GMZ2 was well tolerated and
immunogenic, and reduced the incidence of malaria… for the vaccine to have a public health role. …

Efficacy of RTS, S/AS01E vaccine against malaria in children 5 to 17 months of age

P Bejon, J Lusingu, A Olotu, A Leach… - … England Journal of …, 2008 - Mass Medical Soc
… We conducted a double-blind, randomized trial of RTS,S/AS01E vaccine as compared with
children to receive either the candidate malaria vaccine or a licensed rabies vaccine in a 1:1 …

Seven-year efficacy of RTS, S/AS01 malaria vaccine among young African children

A Olotu, G Fegan, J Wambua… - … England Journal of …, 2016 - Mass Medical Soc
… In an analysis that was not prespecified, we used data from 870 children who were under
active surveillance in the same trial area to determine exposure indexes and categorized the …

[HTML][HTML] Safety and immunogenicity of the RTS, S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan …

L Otieno, YG Mendoza, S Adjei, T Agbenyega… - Vaccine, 2020 - Elsevier
… -infected children on ART [13]. Here, we report results of RTS,S/AS01 vaccination in a small
subset of children … controlled efficacy trial which enrolled more than 15,000 children in seven …