… of clinical malaria among 223 children randomly assigned to the RTS,S/AS01 group and
992 episodes among 224 children randomly assigned to the control group. The vaccine efficacy…

… whether vaccination could reach additional children who are at risk from … vaccine demonstrated
39.0% (95% CI 34.3–43.3%) protective efficacy against clinical malaria in young children …

… in malaria vaccine development in the past 5 years: reasons for cautious optimism, the type
of vaccine … Initiative, which is funding an efficacy trial of RTS,S in children aged 1–4 years in …

… advance in malaria control. Moreover, additional interventions—specifically, effective malaria
vaccines—will be needed to eliminate malaria in the large areas of Africa where malaria …

… The report also stated that some population groups are at considerably higher risk of
contracting malaria and developing severe disease: infants, children under 5 years of age, …

… chemoprevention (SMC), which involves administration of a full course of malaria treatment
to young children at monthly intervals during the high transmission season, is proving to be …

… children who were definitely exposed to malaria infection (ie, children who had either
asymptomatic parasitemia or an episode of clinical malaria) [26]. This effectively excludes the …

… cases of clinical malaria over a 3–4 year period in young infants and children when administered
… Thus, the vaccine has the potential to make a substantial contribution to malaria control …

… a malaria vaccine: at risk, malaria-experienced children living in an area of intense malaria
… being the efficacy of the vaccine, results should be broadly generalisable to children of the …

… malaria vaccine development efforts, with particular emphasis on the impact of the possible
availability of a first generation malaria vaccine in the … The younger children are aligned with …