Challenges and strategies for developing efficacious and long-lasting malaria vaccines

JG Beeson, L Kurtovic, C Dobaño, DH Opi… - Science translational …, 2019 - science.org
… progress toward reducing the global malaria burden (1). The … a strategic goal of developing
malaria vaccines with >75% efficacy against clinical malaria and suitable for use in all malaria

[HTML][HTML] Progress and challenges for malaria vaccines

TL Richie, A Saul - Nature, 2002 - nature.com
… -mosquito-stage vaccine aimed at preventing the transmission of malaria from one …
challenges faced in developing these vaccines, why we believe that success is likely, the strategies

Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities

AJ Birkett, VS Moorthy, C Loucq, CE Chitnis… - Vaccine, 2013 - Elsevier
… of the state of current malaria vaccine development efforts, with … availability of a first generation
malaria vaccine in the near future… strategic guidance document informing malaria vaccine

[HTML][HTML] Progress and challenges towards the development of malaria vaccines

KKA Tetteh, SD Polley - BioDrugs, 2007 - Springer
… for vaccine development. There is now a real possibility of producing a malaria vaccine
licensed for … However, this positive outlook must be tempered with the challenges facing vaccine

Malaria vaccines: current situation, challenges and strategy for the future; a developer''s perspective from the PATH Malaria Vaccine Initiative

C Loucq - Clinical Practice, 2010 - search.proquest.com
… aspects of malaria vaccine development. Our approach to malaria vaccine development is
now … vaccine candidate; the definition of the vaccine that will be needed to complement other …

[HTML][HTML] Strategies for designing and monitoring malaria vaccines targeting diverse antigens

AE Barry, A Arnott - Frontiers in immunology, 2014 - frontiersin.org
… the development of a vaccine that provides broad protection … the challenge in developing
an effective malaria vaccine will … class of malaria vaccines and the challenges associated with …

The path of malaria vaccine development: challenges and perspectives

C Arama, M Troye‐Blomberg - Journal of internal medicine, 2014 - Wiley Online Library
strategies to develop efficient malaria vaccines. … strategies to overcome some of these
challenges and suggest several approaches for the development of an effective malaria vaccine. …

Human challenge models: tools to accelerate the development of malaria vaccines

MM Cooper, C Loiseau, JS McCarthy… - … Review of Vaccines, 2019 - Taylor & Francis
… Expert opinion: The ability to comprehensively evaluate vaccine efficacy in controlled …
malaria vaccines to the clinic, and inform the development and optimisation of potential vaccines

Blood-stage malaria vaccines—recent progress and future challenges

AL Goodman, SJ Draper - Annals of Tropical Medicine & …, 2010 - Taylor & Francis
… 1, strategies for the clinical development of subunit vaccines have focused on a narrow
selection of candidate antigens; more than half of all blood-stage malaria vaccines in human …

[HTML][HTML] Current challenges and proposed solutions to the effective implementation of the RTS, S/AS01 Malaria Vaccine Program in sub-Saharan Africa: A systematic …

CA Dimala, BT Kika, BM Kadia, H Blencowe - PloS one, 2018 - journals.plos.org
… and to use proper communication strategies to clarify the expectations of stakeholders prior
to the introduction of the malaria vaccine [10,14]. Other strategies proposed were to target …