Exploratory study on application of MALDI-TOF-MS to detect SARS-CoV-2 infection in human saliva

MM Costa, H Martin, B Estellon, FX Dupé… - Journal of Clinical …, 2022 - mdpi.com
MALDI-TOF MS with the collection of salivary samples offers real new perspectives of
SARS-CoV… The non-necessity of RT-qPCR test and the affordable cost of the MALDI-TOF MS …

Superiority of MALDI-TOF mass spectrometry over real-time PCR for SARS-CoV-2 RNA detection

M Rybicka, E Miłosz, KP Bielawski - Viruses, 2021 - mdpi.com
SARS-CoV-2 virus in … SARS-CoV-2 Panel, we were able to detect SARS-CoV-2 in low
viral load specimens indicating that supposed negative patients are probably carrying SARS-CoV-…

A combined approach of MALDI-TOF mass spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs

MF Rocca, JC Zintgraff, ME Dattero, LS Santos… - Journal of virological …, 2020 - Elsevier
… These preliminary results suggest that MALDI-TOF MS coupled with ClinPro Tools software
could represents an interesting alternative for diagnosis of SARS-CoV-2 virus as long as we …

RT‐PCR/MALDITOF mass spectrometry‐based detection of SARSCoV‐2 in saliva specimens

MM Hernandez, R Banu, P Shrestha… - Journal of medical …, 2021 - Wiley Online Library
CoV-2 real-time RT-PCR Test (Roche). Together, we demonstrate that saliva represents an
appropriate matrix for SARS-CoV… sensitive and reliable platform for SARS-CoV-2 detection in …

Development of a clinical MALDI-ToF mass spectrometry assay for SARS-CoV-2: Rational design and multi-disciplinary team work

RK Iles, R Zmuidinaite, JK Iles, G Carnell, A Sampson… - Diagnostics, 2020 - mdpi.com
… Utilizing MALDI-ToF mass spectrometric detection to viral envelope glycoproteins in a …
a multifaceted clinical MALDI ToF MS screening test, primarily (but not limited to) SARS-CoV-2, …

MALDI MS-based investigations for SARS-CoV-2 detection

M Preianò, S Correnti, C Pelaia, R Savino… - BioChem, 2021 - mdpi.com
… that derive from MALDI-based approaches for the detection of SARS-CoV-2 and its variants,
we extensively examined the most promising proofs of concept for MALDI studies related to …

Use of MALDI-TOF mass spectrometry for virus identification: a review

T Do, R Guran, V Adam, O Zitka - Analyst, 2022 - pubs.rsc.org
… Although the recent review by Griffin and Downard 35 covered MS-based methods, including
MALDI, it was strictly concentrated on SARS-CoV-2, whereas in this critical review, we …

Detection of SARS-CoV-2 infection in human nasopharyngeal samples by combining MALDI-TOF MS and artificial intelligence

M Deulofeu, E García-Cuesta, EM Peña-Méndez… - Frontiers in …, 2021 - frontiersin.org
… is a MALDI-TOF mass spectral pattern (fingerprint) that can be assigned as a signature
accurately characterizing negative and positive samples for SARS-CoV-… samples of SARS-CoV-2 …

Isothermal gene amplification coupled MALDI-TOF MS for SARS-CoV-2 detection

G Han, Q Lin, J Yi, Q Lyu, Q Ma, L Qiao - Talanta, 2022 - Elsevier
… eRCA) combined MALDI-TOF MS assay for SARS-CoV-2 detection… 1 ab (orf1ab) genes of
SARS-CoV-2 in a single test within 30 … SARS-CoV-2 from other coronaviruses, like SARS-CoV, …

Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection

L Kollhoff, M Kipping, M Rauh, U Ceglarek, G Barka… - Clinical Proteomics, 2023 - Springer
… of virus-specific peptides from SARS-CoV-2 nucleoprotein via magnetic antibody beads. Our
MALDI-TOF-MS method allows the detection of SARS-CoV-2 … MALDI-TOF mass spectra are …