Normal vs. Malignant hematopoiesis: the complexity of acute leukemia through systems biology

J Enciso, L Mendoza, R Pelayo - Frontiers in genetics, 2015 - frontiersin.org
… of auxiliary strategies for leukemia treatment, normal hematopoiesis rebounding, and relapse
… of malignant hematopoiesis and provide helpful platforms for new testable hypotheses. …

[PDF][PDF] Normal and malignant hematopoiesis

M Fey - Annals of oncology, 2007 - boris.unibe.ch
… The role of hematopoietic transcription factors was, however, increasingly gleaned from the
… of human acute leukemias. Many chromosomal translocations in acute leukemias affect …

Epigenetic regulation of normal and malignant hematopoiesis

KL Rice, I Hormaeche, JD Licht - Oncogene, 2007 - nature.com
… Elucidating the mechanisms of aberrant epigenetic deregulation in specific hematological
malignancies including acute promyelocytic leukemia (APL), lymphoma and myelodysplasia …

Epigenetics in normal and malignant hematopoiesis: An overview and update 2017

S Goyama, T Kitamura - Cancer science, 2017 - Wiley Online Library
… exhibited increased extramedullary hematopoiesis. Combined expression of … hematopoietic
cells produced acute leukemia. Importantly, genetic deinduction of IDH2-R140Q in leukemic

Role of HDACs in normal and malignant hematopoiesis

P Wang, Z Wang, J Liu - Molecular cancer, 2020 - Springer
… many different types of malignant hematopoietic diseases, such as lymphoma and leukemia
[11]. … gene expression during hematopoiesis or hematological malignancies, followed by a …

Evidence for malignant transformation in acute myeloid leukemia at the level of early hematopoietic stem cells by cytogenetic analysis of CD34+ subpopulations

D Haase, M Feuring-Buske, S Konemann, C Fonatsch… - 1995 - ashpublications.org
… for the identification of leukemic cells in subpopulations of … leukemic blasts were CD34-. It
was our aim to determine the level of malignant transformation in AML within the hematopoietic

The role of microRNAs in normal and malignant hematopoiesis

D Vasilatou, S Papageorgiou, V Pappa… - European journal of …, 2010 - Wiley Online Library
… 16-1 in chronic lymphocytic leukemia, the increased levels of … levels of mir-181 in acute
myeloid leukemia M1 and M2. The … normal hematopoiesis and hematopoietic malignancies and, …

Tumor suppressor genes in normal and malignant hematopoiesis

U Krug, A Ganser, HP Koeffler - Oncogene, 2002 - nature.com
… as hematopoietic abnormalities become more malignant such as going from the chronic phase
to the blast crisis of chronic myeloid leukemia. … in hematological malignancies, especially …

Adipocytes in hematopoiesis and acute leukemia: friends, enemies, or innocent bystanders?

J Zinngrebe, KM Debatin, P Fischer-Posovszky - Leukemia, 2020 - nature.com
… role of MAT in malignant hematopoiesis, … leukemia research in the context of
metabolism-induced modifications of MAT and other adipose tissues and how this might impact on …

Sex differences in normal and malignant hematopoiesis

X Cui, X Zhao, Y Liang - Blood Science, 2022 - journals.lww.com
… In both healthy and malignant hematopoiesis, there is sex … in the majority of malignant
hematopoiesis than females. … the sex discrepancy in hematologic malignancy. Both research and …