LA Solt, MJ May - Immunologic research, 2008 - Springer
… The Nuclear Factor-kappa B (NF-κB) family of transcription factors … NF-κB activity occurs in a number of chronic inflammatory diseases and certain types of cancers making NF-κB …
… Nuclear factor κB (NF-κB) is a dimeric transcription factor constituted by two of five protein … , cytokines, transcription factors, and regulatory proteins. Since NF-κB is expressed in almost …
D Krappmann, E Wegener, Y Sunami… - … and cellular biology, 2004 - Am Soc Microbiol
… In conclusion, this study defines a novel type of cross talk between the transcription factors of the NF-κB and AP-1 families in the innate immune reaction elicited by LPS. Through …
N Faumont, S Durand-Panteix, M Schlee… - Journal of …, 2009 - Am Soc Microbiol
… LMP1 efficiently counteracts the transcriptional repression of … governed by one single mastertranscriptional system that is c… main mastertranscriptional systems, c-Myc and Rel/NF-κB. …
… achieved mainly by activating the NF-κB pathway, which induces the transcription of a set of … is lethal only if the NF-κB signaling pathway is inhibited. Because NF-κB has a crucial role in …
… quantitative genome-wide analysis of transcriptional regulation of the cellular antiviral response. … and NFκB with Mediator throughout the genome and implicates additional transcription …
… the role of the transcriptional regulator NF-κB in EMT of … TGFβ) activated NF-κB/RELA proto-oncogene, NF-κB subunit (RELA… We conclude that RELA is a mastertranscriptional …
JP Mitchell, RJ Carmody - International review of cell and molecular …, 2018 - Elsevier
… The NF-κBtranscription factor was discovered 30 years ago and has since emerged as the master regulator of inflammation and immune homeostasis. It achieves this status by means …
… degradation of IκB and the release of heterodimers of the mastertranscription factor NF-κB. … Transcription of p100 allows full activation of the alternate NF-κB pathway through IKKα-…