… Aβ-fibers form synapse-like structures in lamina II [23], [24], [25] and novel mono- or
polysynaptic Aβ fiber… These results suggest that the extended Aβ-fibers transmit an innocuous …

… soluble Aβ (sAβ) could degrade fAβ as well. We demonstrate that matrix metalloproteinase-9
(MMP… Proteolytic digests of purified fAβ were analyzed with matrix-assisted laser desorption …

… fibrous proteins (collagens and elastin fibres), glycoproteins (… accumulation of partially
degraded elastin fibres in ECM - is … marked reduction in the levels of Aβ and APP in the cortex and …

… in brain proteolytic systems, such as matrix metalloproteinases.13 These data reveal that
ECM … They inhibit Aβ fibril formation and facilitate the hydrolysis of existing Aβ fibers. These …

… Tenascin-X has elastic properties and associates with both collagen fibrils and elastic
fibers [39]. All multimeric assemblies of the Aβ peptide bound to procollagen C-proteinase …

… The treatment was also able to enhance fibers sprouting from the contralateral cortex … ,
nearby the Aβ deposits. The evidence suggests that PNNs in juxtaposition to the Aβ plaques were …

… Matrix metalloproteinases (MMPs) and proteins containing a disintegrin and metalloproteinase
… Four tissue inhibitors of metalloproteinases (TIMPs) regulate metalloproteinase activity. …

… Structural domains of the matrix metalloproteinases. … (Aβ) collects as plaques after processing
of amyloid precursor protein (APP) by alpha and beta secretase. Plaque formation of Aβ …

… Matrix metalloproteases (MMPs) comprise a large family of zinc endopeptidases that have
been implicated in the generation of neuroinflammation via cleavage of extracellular matrix …

… MBP and NF-L performed the best in discriminating SVD from controls, while T-tau and Aβ
1-… P-tau 181, and Aβ 1-42), white matter lesions (NF-L and MBP) and matrix remodeling (MMP-…