Axonal growth towards Xenopus skin in vitro is mediated by matrix metalloproteinase activity

D Tonge, N Zhu, S Lynham, P Leclere… - European Journal of …, 2013 - Wiley Online Library
axonal growth towards skin explants of Xenopus laevis in matrigel is associated with expression
of matrix metalloproteinase (… -7 cell aggregates enhances axonal growth from Xenopus …

Matrix metalloproteinases during axonal regeneration, a multifactorial role from start to finish

L Andries, I Van Hove, L Moons, L De Groef - Molecular neurobiology, 2017 - Springer
… c At last, MMPs are also upregulated during the final stages of axon regeneration when the
axon growth cone reaches the denervated target neurons. (8) This, together with the fact that …

MMP-mediated modulation of ECM environment during axonal growth and NMJ development

ZCK Chan, MJ Oentaryo, CW Lee - Neuroscience letters, 2020 - Elsevier
… ECM proteins by matrix metalloproteinases (MMPs) during distinct processes in neuromuscular
development, including axonal growth, synaptic formation, elimination and maintenance. …

Matrix metalloproteinases and proteoglycans in axonal regeneration

MA Pizzi, MJ Crowe - Experimental neurology, 2007 - Elsevier
… These proteoglycans inhibit axonal growth in vitro and in vivo. Matrix metalloproteinases (MMPs)
can degrade the core protein of some CSPGs as well as other growth-inhibitory …

Functional interaction between matrix metalloproteinase-3 and semaphorin-3C during cortical axonal growth and guidance

B Gonthier, C Nasarre, L Roth, M Perraut… - Cerebral …, 2007 - academic.oup.com
metalloproteinases. Here, we analyzed the putative functional interaction of matrix
metalloproteinases (MMPs) with guidance cues of the semaphorin family during growth and …

Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth

H Hayashita-Kinoh, H Kinoh, A Okada, K Komori, Y Itoh… - 2001 - AACR
… Expression of membrane-type (MT) 5 matrix metalloproteinase (… it was localized at the edge
of growth cone. Proteoglycans inhibit … may play a role in axonal growth that contributes to the …

Matrix metalloproteinase‐3 in the central nervous system: a look on the bright side

I Van Hove, K Lemmens, S Van de Velde… - Journal of …, 2012 - Wiley Online Library
… -3 in axonal growth should be encouraged as this MMP seems to be a potential candidate
protease necessary to overcome the inhibitory environment and to support axonal regrowth …

Matrix metalloproteinase-2 and-9 as promising benefactors in development, plasticity and repair of the nervous system

M Verslegers, K Lemmens, I Van Hove… - Progress in neurobiology, 2013 - Elsevier
Matrix metalloproteinases (MMPs) … growth cone, MMP-9 can regulate axonal guidance
through EphB2 cleavage when associated with its ligand EphrinB2 on a neighboring cell/growth

Extracellular matrix and matrix metalloproteinases in sciatic nerve

CI Platt, CA Krekoski, RV Ward… - Journal of …, 2003 - Wiley Online Library
… neurite outgrowth in vitro, including growth factors, cell adhesion molecules … axonal growth
with attendant changes in gene expression and cellular metabolism. Axonal sprouts or growth

Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co‐regulate axonal outgrowth of mouse retinal ganglion cells

D Gaublomme, T Buyens, L De Groef… - Journal of …, 2014 - Wiley Online Library
… 5a–f), where it appeared in a patchy pattern all over the axon and was also present at the
level of the axon growth cone (inset Fig. 5d–f). Expression of MT1-MMP was highly present in …