[PDF][PDF] Matrix metalloproteinases (MMPs) in health and disease: an overview

CJ Malemud - Front Biosci, 2006 - article.imrpress.com
Matrix metalloproteinases (MMPs) are members of an enzyme family that require a zinc ion
MMPs are critical for maintaining tissue allostasis. MMPs are active at neutral pH and can …

Matrix metalloproteinases (MMPs) in oral diseases

T Sorsa, L Tjäderhane, T Salo - Oral diseases, 2004 - Wiley Online Library
matrix metalloproteinases (MMPs). Our research groups have for years been working to
evaluate the presence, activity, function and regulation of MMPs … agents for MMP inhibition in the …

Multifaceted role of matrix metalloproteinases (MMPs)

D Singh, SK Srivastava, TK Chaudhuri… - Frontiers in molecular …, 2015 - frontiersin.org
Matrix metalloproteinases (MMPs) are described as calcium-dependent zinc … MMPs have
been demonstrated in extracellular matrix (ECM) degradation and remodeling of tissues. MMPs

Matrix metalloproteinases (MMPs): Chemical–biological functions and (Q) SARs

RP Verma, C Hansch - Bioorganic & medicinal chemistry, 2007 - Elsevier
Matrix metalloproteinases (MMPs) are a large family of … matrix (ECM), including collagens,
elastins, gelatin, matrixMMPs are excreted by a variety of connective tissue and pro-…

Assays of matrix metalloproteinases (MMPs) activities: a review

C Lombard, J Saulnier, J Wallach - Biochimie, 2005 - Elsevier
… in the case of the matrix metalloproteinases (MMPs), as their … , structural components of
extracellular matrices. They are … In the case of studies aimed at determining the role of MMPs, …

Matrix metalloproteinases (MMPs)

CT Supuran, A Scozzafava - Proteinase and peptidase inhibition …, 2002 - books.google.com
… some specific MMPs. Bacterial collagenase inhibitors structurally related to the hydroxamate
MMP inhibitors are also discussed. Clinical trials of some potent MMP inhibitors showed …

The role of matrix metalloproteinases (MMPs) in human caries

C Chaussain-Miller, F Fioretti… - Journal of dental …, 2006 - journals.sagepub.com
matrix metalloproteinases (MMPs) in the caries process and to discuss new therapeutic
avenues. MMPs hydrolyze components of the extracellular matrixMMPs have been suggested to …

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion

D Bourboulia, WG Stetler-Stevenson - Seminars in cancer biology, 2010 - Elsevier
… enzymes, including matrix metalloproteinases (MMPs). Among other roles, MMPs degrade
the … Tissue inhibitors of metalloproteinases or TIMPs control MMP activities and, therefore, …

Matrix metalloproteinases

O Zítka, J Kukacka, S Krizkov, D Húska… - Current medicinal …, 2010 - ingentaconnect.com
MMPs are zinc and calcium-dependent endopeptidases, … -associated MMPs (MT-MMPs),
this prevents MMPs from cleaving … MMP-19, MMP-20, MMP-27 and MMP-12 are considered to …

Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs

A Jabłońska-Trypuć, M Matejczyk… - Journal of enzyme …, 2016 - Taylor & Francis
… degradation in extracellular matrix (ECM) are matrix metalloproteinases (MMPs). Collagen
is … Typical structure of MMPs consists of several distinct domains. MMP family can be divided …