… Mostly for viral infections antigen specific T cells are produced and target to virally infected
cells. In SARS-CoV-2 infections CD8 + T cell response is important to kill virally infected cells (…

… Using potent antigens in combination with strong adjuvants may effectively trigger the
activation of specific MERS-CoV cellular responses as well as the production of neutralizing …

… Here we show that patient 1 did not express IRF3 in response to MERS-CoV and secreted
low levels of IFNα but high levels of IL-17, in the lungs and serum. Conversely, patient 2 …

… with exposure to dromedaries had MERS-CoV specific T-cell responses, but of 20 abattoir
… had such T-cell responses. No individuals with MERS-CoV T-cell responses had detectable …

… CD8+ T cells responses (84). Moreover, the age-dependent reduction in the magnitude of T
cell response may also explain the higher susceptibility to SARS-CoV with advanced age (85…

… T cell ICS was performed after stimulating lung cells with a 1-μM concentration of specific
peptide. MERS-CoV–specific CD8 + and CD4 + T cell responses were identified using …

… Vero E6 cells are permissive cells for MERS-CoV, and our results demonstrated that
VSVΔG-eGFP-MERS and VSVΔG-MERS could infect Vero E6 cells and form large syncytia (Figs. 1…

… shed light on MERS coronavirus (MERS-CoV). It has been confirmed that T-cell immunity
plays … For MERS-CoV-specific T-cell responses, PBMCs obtained on day 24 after illness onset …

… Our results, which demonstrated no MERS-CoV-specific PRNT 50 or T cell responses in
healthy controls, are consistent with others that show only very low levels of MERS-CoV …

… Citation74 In summary, TLRs play a crucial role in restricting coronavirus replication and
initiating immune responses. Although coronavirus activates the TLR signaling pathway, the …