… since traditional immunization pathways require booster doses to … immunization dose
spacing. In this study, we aimed to optimize the immunization dosage and interval of a MERS-CoV …

… dose for MERS subunit vaccines. In this study, we examined the immunization potential of
different doses … neutralizing antibodies against infection of MERS-CoV, using S377-588-Fc as …

… Antibody titres tended to be either low or undetectable after the first dose of DNA but were
boosted 10-fold after immunization with S1 protein. Two doses of S1 protein achieved an IC 90 …

… We further demonstrated that single-dose immunization, either by the intramuscular or
intranasal route, induced a high-level and lasting MERS-CoV-specific neutralizing antibodies and …

… 14 days of whole-course immunization, and the vaccine was … induced similar dose-dependent
SARS-CoV-2 and geometric … with SARS-CoV-2 only need a single dose of BNT162b2 to …

… It has been shown that an anti-MERS-CoV polyclonal … -immunized transchromosomic (Tc)
cattle inhibits MERS-CoV … doses, injection doses, or immunization routes, MERS-CoV S/…

… between single-dose immunization with UV light-inactivated MERS-CoV and PIV5-MERS-S. …
We observed more eosinophils in the lungs of mice immunized with inactivated MERS-CoV …

… complete protection against MERS-CoV infection, with the lowest dosage and least injection
… in immunized camels. In addition, immunized NHPs were protected against MERS-CoV …

… immunized with a single dose of the MERS-CoV vaccine strain (EMC2012-CA 22 C) at a
dosage of 2 … Four weeks after vaccination, sera were collected from a subset of immunized K18-…

… dose administered via the in route, the level of IgG was relatively low [94]. After several
doses over 6 months, the titers of MERS-CoV… of immunized mice was generated by MERS-CoV-…