Deciphering the COVID‐19 cytokine storm: systematic review and metaanalysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
… Elevated cytokines and suppressed immune responses have been hypothesized to set off
a cytokine storm, contributing to ARDS, multiple-organ failure and, in the most severe cases, …

[HTML][HTML] Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
… This study concluded that the cytokine storm is associated with COVID-19 severity, likely
through increased pulmonary pathology, T cell depletion, and CD4+ T cell dysfunction. …

[HTML][HTML] Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes

DE Leisman, L Ronner, R Pinotti, MD Taylor… - The Lancet …, 2020 - thelancet.com
… Our findings question the role of a cytokine storm in COVID-19-induced organ dysfunction.
Many questions remain about the immune features of COVID-19 and the potential role of anti-…

[HTML][HTML] Association of pregnancy with coronavirus cytokine storm: systematic review and meta-analysis

J Muthuka, M Kiptoo, K Oluoch, JM Nzioki… - JMIR Pediatrics and …, 2022 - pediatrics.jmir.org
… in this meta-analysis. Studies reporting pregnancy status and comparing the COVID-19 …
cytokine storm outcome were included. COVID-19 severity characterized by a cytokine storm was …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… is an urgent need to understand the cytokine storm in COVID-19. … cytokine storm induced
by COVID-19. In addition, we suggest that the identification and treatment of the cytokine storm

[HTML][HTML] Meta-analysis informed machine learning: Supporting cytokine storm detection during CAR-T cell Therapy

A Bogatu, M Wysocka, O Wysocki, H Butterworth… - Journal of Biomedical …, 2023 - Elsevier
… Then, a 14 cytokine enzyme-linked immunosorbent assay (SP-… cytokine levels associated
with cytokine storms. Four ELISA assays were validated, enabling the detection of 14 cytokines

[PDF][PDF] Cytokines as predictors of COVID-19 severity: evidence from a meta-analysis

Ł Szarpak, B Nowak, D Kosior, A Zaczynski… - Pol Arch Intern …, 2021 - researchgate.net
… This phenomenon is the so-called cytokine storm caused by an abnormal over-response of
the immune system. Cytokine storms are common complications of COVID-19 and influenza …

[HTML][HTML] Description and analysis of cytokine storm in registered COVID-19 clinical trials: a systematic review

K Eljaaly, H Malibary, S Alsulami, M Albanji, M Badawi… - Pathogens, 2021 - mdpi.com
… Therefore, the objective of this systematic review was to describe the variability in
identifying patients with cytokine storm in clinical trials of COVID-19 patients and the relevant …

[HTML][HTML] Hazards of the cytokine storm and cytokine-targeted therapy in patients with COVID-19

M Quirch, J Lee, S Rehman - Journal of medical Internet research, 2020 - jmir.org
cytokines in a positive feedback loop of pathogen-triggered inflammation. Currently, cytokine
storm … Objective: The aim of this paper is to study the cytokine storm response in SARS-CoV-…

[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… identify the cytokine storm. In this review, we referred COVID-19 associated cytokine storm as
… patients who are severely ill along with a high concentration of pro-inflammatory cytokines. …