Importance Many studies have demonstrated an association between early-life adversity (ELA)
and executive functioning in children and adolescents. However, the aggregate …

… an early onset of MDD (ie, during childhood or adolescence) is not known. In this meta-analysis…
associations between ELS and the risk for onset of MDD before age 18 years. In addition, …

… Early life adversities (ELAs) are associated with an increased risk of psychopathology,
with studies suggesting a relation to structural brain alterations. Given the recently growing …

… Having focused on reactivity to social stressors, which are potent inducers of HPA responses
due to their elements of social-evaluative threat and uncontrollability 20 , this meta-analysis …

… Overview of the meta-analysis We meta-analyzed relevant studies on early-life stress and risk,
time, and … Our first goal was to quantify the associations between early-life stress and adult …

… For the purpose of the meta-analysis, studies that provided risk ratios were converted to
odds ratio using the formula (Grant, 2014): O R = ( 1 − p ) × R R ( 1 − R R ) × p Where OR is the …

… this meta-analysis, we decided to isolate the effects of deprivation (including neglect and
early life … sex characteristics earlier and experience earlier age at menarche than non-Hispanic …

… Early life adversity is a major public health problem experienced by over 19.4 million children.
Children with a history of early adversity are at a greater risk … early adversity increases risk …

… Therefore, while the goal of this meta-analysis was to hone in on the ELS-cortisol … in
identifying risk for psychopathology later in life, in our future work we plan to conduct a meta-analysis …

… In a series of meta-analyses, we found some evidence that both … early adversity is associated
with higher levels of OXTRm (r = .02), and that adults who report lower levels of childhood …