The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

PD Fransquet, J Wrigglesworth, RL Woods, ME Ernst… - … epigenetics, 2019 - Springer
epigenetic clock calculators that met our inclusion criteria [6, 31,32,33,34,35,36,37,38,39,40].
A further 21 studies were excluded because they did not measure an appropriate outcome. …

Tracking the epigenetic clock across the human life course: a meta-analysis of longitudinal cohort data

RE Marioni, M Suderman, BH Chen… - The Journals of …, 2019 - academic.oup.com
… As there is evidence for differences based on the epigenetic clock in other … an analysis of
longitudinal trajectories of the epigenetic clock across the life course, showing that epigenetic

A systematic review and meta-analysis of epigenetic clocks in schizophrenia

JH Chrusciel, R Orso, BP de Mattos, GR Fries… - Schizophrenia …, 2022 - Elsevier
… Our findings suggest that the method of epigenetic clocks is a critical factor associated with
estimates of aging acceleration in SZ. However, more studies are needed to confirm these …

[HTML][HTML] A systematic review of biological, social and environmental factors associated with epigenetic clock acceleration

L Oblak, J van der Zaag, AT Higgins-Chen… - Ageing research …, 2021 - Elsevier
epigenetic clocks. Subsequently, we created an extensive dataset of over 1300 study findings
in which epigenetic clocks … relationship between these clocks and numeral environmental …

The role of epigenetic clocks in explaining educational inequalities in mortality: A Multicohort study and meta-analysis

G Fiorito, S Pedron, C Ochoa-Rosales… - The Journals of …, 2022 - academic.oup.com
… changes in blood captured by epigenetic clocks in explaining these inequalities. Data were
… , DNAmPhenoAge, and DNAmGrimAge epigenetic clocks were assessed in each cohort via …

A systematic review and meta-analysis of environmental, lifestyle, and health factors associated with DNA methylation age

J Ryan, J Wrigglesworth, J Loong… - The Journals of …, 2020 - academic.oup.com
… by the epigenetic clock (rather than the inverse), that meant excluding studies that measured
the epigenetic clock at baseline and tracked disease incidence or mortality over time. …

Biological clocks as age estimation markers in animals: a systematic review and metaanalysis

LS Le Clercq, A Kotzé, JP Grobler… - Biological …, 2023 - Wiley Online Library
… that these species may be well suited to the development of epigenetic clocks for age … in
pinnipeds that enabled the construction of an epigenetic clock, from combined skin and blood …

A meta-analysis of genome-wide association studies of epigenetic age acceleration

J Gibson, TC Russ, TK Clarke, DM Howard… - PLoS …, 2019 - journals.plos.org
… age acceleration measures, based on the Horvath and Hannum epigenetic clocks. We …
CpG sites to be included in each of these epigenetic clocks, there is limited overlap in the CpGs …

[HTML][HTML] DNA methylation-based measures of biological age: meta-analysis predicting time to death

BH Chen, RE Marioni, E Colicino, MJ Peters… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
… Our study strongly suggests IEAA is reflective of an intrinsic epigenetic clock that is associated
with mortality independent of chronological age, changes in blood cell composition, and …

The epigenetic clock and telomere length are independently associated with chronological age and mortality

RE Marioni, SE Harris, S Shah… - International journal …, 2016 - academic.oup.com
… The epigenetic clock changed over time at … epigenetic clock estimates and telomere
length. Telomere length explained 6.6% of the variance in age in LBC1936, the epigenetic clock