Systematic Review: Why sources of heterogeneity in meta-analysis should be investigated

SG Thompson - Bmj, 1994 - bmj.com
… This paper distinguishes between the concepts of clinical and statistical heterogeneity
and exemplifies the importance of investigating heterogeneity by using published meta-analyses

Exploring heterogeneity

JPT Higgins, T Li - … Reviews in Health Research: MetaAnalysis …, 2022 - Wiley Online Library
… underlying question, plans should be made when writing the meta- analysis protocol for a
careful investigation of potential sources of heterogeneity (see Chapter 2). When faced with …

Meta-analyses: what is heterogeneity?

P Sedgwick - Bmj, 2015 - bmj.com
… and participants to detect heterogeneity. To formally investigate heterogeneity across the …
of intervention (hospital v community) investigated whether the effect of the intervention on …

Investigating underlying risk as a source of heterogeneity in metaanalysis

SG Thompson, TC Smith, SJ Sharp - Statistics in medicine, 1997 - Wiley Online Library
investigation of heterogeneity in a meta-analysis. Analyses attempting to investigate the …
In this paper we show how such analyses are flawed, and discuss the main determinants of …

Quantifying heterogeneity in a metaanalysis

JPT Higgins, SG Thompson - Statistics in medicine, 2002 - Wiley Online Library
heterogeneity in a meta-analysis that overcome the shortcomings of existing measures. Our
focus is on the impact of heterogeneity on the results of a meta-analysis … those investigated

Detecting and describing heterogeneity in metaanalysis

RJ Hardy, SG Thompson - Statistics in medicine, 1998 - Wiley Online Library
… The investigation of heterogeneity is a crucial part of any meta-analysis. While it has been
stated … We conclude that the test of heterogeneity should not be the sole determinant of model …

Metaanalysis of the effectiveness of chronic care management for diabetes: investigating heterogeneity in outcomes

AMJ Elissen, LMG Steuten… - Journal of Evaluation …, 2013 - Wiley Online Library
… is investigated as a potential cause of heterogeneity in results … Meta-analysis and meta-regression
will be used to … as to investigate the three potential sources of heterogeneity described …

Investigating heterogeneity in an individual patient data metaanalysis of time to event outcomes

CT Smith, PR Williamson, AG Marson - Statistics in medicine, 2005 - Wiley Online Library
investigation of potential sources of heterogeneity and enables a fuller analysis of time to event
outcomes in metaanalysis… the evidence for heterogeneity in metaanalysis and examine …

Explaining heterogeneity in metaanalysis: a comparison of methods

SG Thompson, SJ Sharp - Statistics in medicine, 1999 - Wiley Online Library
meta-analysis. This paper compares a number of methods which can be used to investigate
… for each study in the meta-analysis, explains any heterogeneity. The main example is from a …

Heterogeneity in meta-analysis: a comprehensive overview

D Stogiannis, F Siannis, E Androulakis - The International Journal of …, 2024 - degruyter.com
… to appropriately investigate the various sources of heterogeneity [10]. … heterogeneity and
random-effects analysis. We also discuss the heterogeneity problem in the field of meta analysis