Direct oral anticoagulants in the treatment of acute venous thromboembolism: a systematic review and meta-analysis

A Gómez-Outes, AI Terleira-Fernández… - Thrombosis research, 2014 - Elsevier
… We systematically reviewed and meta-analysed clinical outcomes with direct oral anticoagulants
(DOAC: dabigatran, rivaroxaban, apixaban or edoxaban) for treatment of acute VTE. …

New oral anticoagulants in elderly adults: evidence from a metaanalysis of randomized trials

P Sardar, S Chatterjee, S Chaudhari… - Journal of the …, 2014 - Wiley Online Library
oral anticoagulants (NOACs) such as rivaroxaban, dabigatran, and apixaban have been
developed as an alternative to conventional anticoagulants… of the present meta-analysis were to …

New oral anticoagulants increase risk for gastrointestinal bleeding: a systematic review and meta-analysis

IL Holster, VE Valkhoff, EJ Kuipers, ETTL Tjwa - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: A new generation of oral anticoagulants (nOAC), which includes
thrombin and factor Xa inhibitors, has been shown to be effective, but little is known about …

Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysis

C van Walraven, RG Hart, DE Singer, A Laupacis… - Jama, 2002 - jamanetwork.com
… Excluding these patients from the analysis did not alter our results. The only study that
randomized patients to receive aspirin or low-intensity oral anticoagulant with aspirin found no …

Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature

F Dentali, N Riva, M Crowther, AGG Turpie, GYH Lip… - Circulation, 2012 - Am Heart Assoc
… Similarly, repeating our analyses with Comprehensive Meta Analysis software including
trials with extremely low or zero event rates did not change the results of the primary analyses (…

[HTML][HTML] Mortality outcomes in patients receiving direct oral anticoagulants: a systematic review and metaanalysis of randomized controlled trials

C Chai‐Adisaksopha, C Hillis, T Isayama, W Lim… - Journal of Thrombosis …, 2015 - Elsevier
analysis may be unable to provide the precise estimates of bleeding risk and consequences
of oral anticoagulant … Therefore, we conducted a metaanalysis that aimed to assess the …

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

CT Ruff, RP Giugliano, E Braunwald, EB Hoffman… - The Lancet, 2014 - thelancet.com
… Our findings offer clinicians a more comprehensive picture of the new oral anticoagulants as
meta-analysis support the premise that compared with warfarin, the new oral anticoagulants

Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled …

BD Fox, SR Kahn, D Langleben, MJ Eisenberg… - Bmj, 2012 - bmj.com
… As far as we know, this study is the first overall analysis of the novel oral anticoagulants for
… By pooling results in this meta-analysis, the upper confidence limit of the relative risk for …

Real-world safety and efficacy of direct oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of 605 771 patients

D Menichelli, F Del Sole, A Di Rocco… - European Heart …, 2021 - academic.oup.com
… To analyse the safety and efficacy of direct oral anticoagulants (DOACs) in real-world …
pair-wise meta-analyses using a random effect model and a random effect network meta-analysis

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

JA López-López, JAC Sterne, HHZ Thom, JPT Higgins… - bmj, 2017 - bmj.com
… , that evaluated the use of a direct acting oral anticoagulant (DOAC), vitamin K antagonist,
or … for oral anticoagulation. Trials in participants only eligible for parenteral anticoagulation