Statin therapy in stroke prevention: a meta-analysis involving 121,000 patients

C O'Regan, P Wu, P Arora, D Perri, EJ Mills - The American journal of …, 2008 - Elsevier
… Using a systematic review of the literature and meta-analytic techniques, we aimed to
quantify the effects of statin therapy on both primary and secondary stroke prevention, and any …

Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy

CP Cannon, BA Steinberg, SA Murphy, JL Mega… - Journal of the American …, 2006 - jacc.org
… standard-dose statin therapy seen in this meta-analysis, not … the percentage of patients on
statins, they should ensure that … meta-analysis also underscores the role of high-dose statins

The efficacy and safety of intensive statin therapy: a meta-analysis of randomized trials

K Josan, SR Majumdar, FA McAlister - Cmaj, 2008 - Can Med Assoc
… We included randomized clinical trials that compared different regimens of statin therapy
compared different intensities of statin therapy but that used much lower statin doses in the …

Primary prevention of cardiovascular diseases with statin therapy: a meta-analysis of randomized controlled trials

P Thavendiranathan, A Bagai… - Archives of Internal …, 2006 - jamanetwork.com
… from statin therapy in our analysismeta-analysis, 8 the mortality rate in the placebo arm was
11.3% over approximately 5.5 years, and the reduction in overall mortality with statin therapy

Safety and efficacy of statin therapy

BB Adhyaru, TA Jacobson - Nature Reviews Cardiology, 2018 - nature.com
therapy or concerns about initiating statin therapy. In this Review, we explore the safety of
statin therapy … about the safety of statins. Overwhelming evidence suggests that the benefits of …

[HTML][HTML] Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

J Armitage, C Baigent, E Barnes, DJ Betteridge… - The Lancet, 2019 - thelancet.com
… In this meta-analysis, randomised trials of statin therapystatin therapy versus control, plus
individual participant data from five trials of more intensive versus less intensive statin therapy (…

Intensive statin therapy compared with moderate dosing for prevention of cardiovascular events: a meta-analysis of> 40 000 patients

EJ Mills, C O'Regan, O Eyawo, P Wu… - European heart …, 2011 - academic.oup.com
Statin therapy is associated with important benefits for … of statins yields larger treatment
effects. We aimed to determine if intensive dosing is clinically important using a meta-analysis of …

Proportion and risk indicators of nonadherence to statin therapy: a meta-analysis

M Lemstra, D Blackburn, A Crawley, R Fung - Canadian journal of …, 2012 - Elsevier
statin therapy have not been found. Because of a well-defined search strategy, our meta-analysis
Also, receiving less lipid testing before statin therapy reflects a lack of knowledge of the …

Meta-analysis: statin therapy does not alter the association between low levels of high-density lipoprotein cholesterol and increased cardiovascular risk

H Jafri, AA Alsheikh-Ali, RH Karas - Annals of internal medicine, 2010 - acpjournals.org
… person-years, despite statin therapy. To put this in context with the magnitude of benefit
from statin therapy, the present analysis suggests that statin therapy is associated with 4 fewer …

Statin therapy and outcome after ischemic stroke: systematic review and meta-analysis of observational studies and randomized trials

D Ní Chróinín, K Asplund, S Åsberg, E Callaly… - Stroke, 2013 - Am Heart Assoc
… For our prespecified secondary analysis of studies of statin therapy at stroke onset in patients
… for inclusion in the secondary analysis of poststroke statin therapy (5 observational studies, …