… NLRP3 inflammasome pathway. Furthermore, we discuss the potential roles of NLRP3 in
metabolic and cognitive diseases… mellitus, Alzheimer’s disease, and major depressive disorder. …

… has been shown to be critical for the development of metabolic diseases, as NLRP3
deficiency resulted in decreased systemic inflammation, reduced immune cell activation and …

… inflammatory disease, whereas aberrant IL-1β secretion through inherited NLRP3 mutations
… In this review, we discuss recent developments in the structure of the NLRP3 inflammasome…

… Since the establishment that nutrient overload coincides with peripheral tissue inflammation
with M1 pro-inflammatory macrophages as important perpetuators of metabolic disease …

… NLRP3 in host defense, NLRP3 inflammasome has been frequently implicated in the progression
of several diseases, including metabolic … is a well-known metabolic disease with clear …

… deleterious effect of hypercaloric diets is reverted by the NLRP3 inflammasome inhibition. …
Recently, the role of NLRP3 inflammasome in obesity, cardiovascular, and metabolic diseases …

… different background or varied degrees of metabolic disease or obesity. Polymorphisms
in the NLRP3 gene have been associated with several diseases, such as Crohn's disease [53], …

… pathway and this finding raised the horizon for other similar research that demonstrates the
link between metabolic diseases like cardiometabolic syndrome and NLRP3 inflammasome …

… Stk24 deficiency in the hematopoietic system promoted HFD-induced metabolic … NLRP3
and intervened in NLRP3 inflammasome assembly, which prevented HFD-induced metabolic …

… NLRP3 inflammasome is a key regulator in inflammation-related diseases and that resveratrol
modulates metabolic … metaflammation relating to NLRP3 inflammasome. Four weeks of …