Molnupiravir for the treatment of non-severe COVID-19: a systematic review and meta-analysis of 14 randomized trials with 34 570 patients

M Sun, H Lai, J Huang, J Liu, Y Li, J Tian… - Journal of …, 2023 - academic.oup.com
… As new trials have been published, the efficacy and safety of molnupiravir need … the efficacy
and safety of molnupiravir for the treatment of non-severe (mild or moderate) COVID-19, and …

Human safety, tolerability, and pharmacokinetics of molnupiravir, a novel broad-spectrum oral antiviral agent with activity against SARS-CoV-2

WP Painter, W Holman, JA Bush… - Antimicrobial agents …, 2021 - Am Soc Microbiol
… of mild, truncal, maculopapular, pruritic rash following multiple BID doses of 800 mg molnupiravir,
… Scaling between efficacious molnupiravir exposures in mouse models of coronavirus

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

SH Khoo, R Fitzgerald, T Fletcher… - Journal of …, 2021 - academic.oup.com
COVID-19 treatments. In this trial (NCT04746183) we evaluated the safety and optimal dose
of molnupiravir … Preliminary data have also been presented from a study in patients with mild

Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19: a meta-analysis

W Wen, C Chen, J Tang, C Wang, M Zhou… - Annals of …, 2022 - Taylor & Francis
molnupiravir has shown promising efficacy and safety in phase I/II/III clinical trials. Studies
have shown that molnupiravir … -hospitalized adults with mild-to-moderate COVID-19 disease …

Effect of molnupiravir on biomarkers, respiratory interventions, and medical services in COVID-19: a randomized, placebo-controlled trial

MG Johnson, A Puenpatom, PA Moncada… - Annals of internal …, 2022 - acpjournals.org
… efficacy and safety of molnupiravir in nonhospitalized adults with mild to moderate COVID-…
potential benefits of molnupiravir for the treatment of mild to moderate COVID-19 based on …

[HTML][HTML] Efficacy and safety of oral antivirals in individuals aged 80 years or older with mild-to-moderate COVID-19: preliminary report from an Italian Prescriber Center

G Bruno, S Perelli, M Giotta, N Bartolomeo… - Le Infezioni in …, 2022 - ncbi.nlm.nih.gov
… We evaluated the safety and effectiveness of oral antivirals in older people with a high
burden of co-morbidities. Randomized trials of molnupiravir and nirmatrelvir showed a lower …

Comprehensive review on molnupiravir in COVID-19: a novel promising antiviral to combat the pandemic

S Khiali, E Khani, SB Rouy… - Future Microbiology, 2022 - Future Medicine
… agents in patients with milder clinical manifestations shows … of molnupiravir in outpatients
with mild to moderate COVID-19. … and safety of molnupiravir in mild to moderate patients with …

[HTML][HTML] Clinical Outcome and 7-Day Virological Clearance in High-Risk Patients with Mild–Moderate COVID-19 Treated with Molnupiravir, Nirmatrelvir/Ritonavir, or …

F Bai, T Beringheli, V Vitaletti, A Santoro, F Molà… - Infectious Diseases and …, 2024 - Springer
… , molnupiravir, and a 3-day course of remdesivir are antiviral therapies recommended in
patients with a mild-to-moderate COVID-19 … We thus investigated the effectiveness, safety, and …

Molnupiravir for Treatment of Adults with Mild or Moderate COVID-19: A Systematic Review and Meta-Analysis

Y Gao, M Liu, Z Li, J Xu, J Zhang… - Available at SSRN …, 2023 - papers.ssrn.com
… effects of molnupiravir in treating COVID-19 remain uncertain. This systematic review aimed
to evaluate the efficacy and safety of molnupiravir for adult patients with mild or moderate …

[HTML][HTML] Effectiveness and adverse events of nirmatrelvir/ritonavir versus molnupiravir for COVID-19 in outpatient setting: multicenter prospective observational study

JJ Park, H Kim, YK Kim, SS Lee, E Jung… - Journal of Korean …, 2023 - ncbi.nlm.nih.gov
… and safety of oral treatments for COVID-19 in Korea. … /ritonavir and those treated with
molnupiravir for COVID-19. The … with molnupiravir, most of them were dysgeusia and were mild. In …