Mitochondrial dysfunction in neurodegenerative diseases

A Johri, MF Beal - Journal of Pharmacology and Experimental …, 2012 - ASPET
Neurodegenerative diseases are a large group of … mitochondrial function as a causative
factor in these diseases. More recently, evidence has emerged for impaired mitochondrial

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

MT Lin, MF Beal - Nature, 2006 - nature.com
… Mutations in mitochondrial DNA and oxidative stress both contribute to … neurodegenerative
diseases. In all major examples of these diseases there is strong evidence that mitochondrial

[HTML][HTML] Mitochondrial dysfunction in neurodegenerative diseases

MF Beal - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1998 - Elsevier
… prototypical neurodegenerative diseases which are associated with either nuclear or
mitochondrial DNA mutations which either directly or indirectly lead to mitochondrial dysfunction. …

Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure

Y Wang, E Xu, PR Musich, F Lin - CNS neuroscience & …, 2019 - Wiley Online Library
neurodegenerative diseases. However, pharmacological agents enhancing mitochondria
integrity to treat neurodegenerative diseases … can enhance mitochondria biogenesis and the …

Mitochondrial dysfunction and biogenesis in neurodegenerative diseases: pathogenesis and treatment

M Golpich, E Amini, Z Mohamed… - CNS neuroscience & …, 2017 - Wiley Online Library
… of the involvement of mitochondrial dysfunction in pathogenesis of neurodegenerative
diseases including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD…

Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases

E Trushina, CT McMurray - Neuroscience, 2007 - Elsevier
… In this review, we consider characteristics of three classes of neurodegenerative
diseases with different, but overlapping links to oxidative damage: Huntington’s disease (HD), …

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

AH Bhat, KB Dar, S Anees, MA Zargar… - Biomedicine & …, 2015 - Elsevier
… (HD), amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). In different
neurodegenerative diseases mitochondrial dysfunction has been considered as the main cause in …

Mitochondrial dysfunction in the development and progression of neurodegenerative diseases

J Johnson, E Mercado-Ayon, Y Mercado-Ayon… - Archives of biochemistry …, 2021 - Elsevier
… Targeting these aspects of mitochondrial dysfunction may present viable therapeutic … the
neurodegenerative diseases. This review aims to summarize the role of the mitochondria in the …

Mitochondrial dysfunction in neurodegenerative diseases and cancer

MB De Moura, LS Dos Santos… - Environmental and …, 2010 - Wiley Online Library
… and is perhaps a direct cause of the disease … to neurodegenerative diseases, and, in the
next section, we will explore how mitochondrial dysfunction and alterations in mitochondrial

Mitochondrial dysfunction in neurodegenerative diseases

AHV Schapira - Neurochemical research, 2008 - Springer
… DNA result in a diverse group of disorders often collectively referred to as the mitochondrial
neurodegenerative diseases caused by mutations of nuclear genes encoding mitochondrial