… antibody cooperativity to develop a therapeutic mAb cocktail against Ebola virus. We systematically analyzed the antibody … that in a two-antibodycocktail, molecular mimicry was a …
Q Wang, H Yang, X Liu, L Dai, T Ma, J Qi… - Science translational …, 2016 - science.org
… antibodies bound to different viral epitopes, suggesting that these antibodies could be used as a therapeutic cocktail… the potential of these antibodies to elicit antibody-dependent cellular …
H Zeng, J Zhang, X Song, J Zeng… - The Journal of …, 2021 - academic.oup.com
… Furthermore, we will study the mechanism of the mAb cocktail in a variety of disease models and will also prepare the immunodominant epitope–specific humanized antibody or the …
V Irani, AJ Guy, D Andrew, JG Beeson… - Molecular …, 2015 - Elsevier
Monoclonal antibodies are being developed as therapeutics to complement drugs and vaccines or to fill the gap where no drugs or vaccines exist. These therapeutic antibodies (ThAb) …
K Haneef, R Saleem, MSI Khan… - Exploration of …, 2021 - explorationpub.com
… Nevertheless, considering therapeutic challenges in the context of the new coronavirus pandemic, this review addresses the molecular mechanism of the immune activation and …
… a monoclonal antibody (mAb) cocktail (ZRC-… cocktail demonstrated effective prophylactic and therapeutic activity against SARS-CoV-2 infection in Syrian hamsters. The antibodycocktail …
KA Kusi, BW Faber, M van der Eijk, AW Thomas… - Malaria journal, 2011 - Springer
… antibodies to epitopes that are common to all antigens was tested in this study. Antibodies to … of induced cross-strain antibodies in comparison with antibodies induced by a multi-allele …
X Qiu, J Audet, M Lv, S He, G Wong, H Wei… - Science translational …, 2016 - science.org
… The human-mouse chimeric monoclonal antibody (mAb) cocktail ZMapp, previously shown to be … We show that a two-antibodycocktail, MIL77E, is fully protective in NHPs when …
… each antibody alone after two weeks. Tab 1 summarized the percentage of growth inhibition of the MAb cocktail in comparison with that of each individual antibody. The MAb cocktail …