Investigation of Pseudomonas aeruginosa quorum-sensing signaling system for identifying multiple inhibitors using molecular docking and structural analysis …

V Soheili, BSF Bazzaz, N Abdollahpour… - Microbial …, 2015 - Elsevier
Pseudomonas aeruginosa is an opportunistic human pathogen and a common Gram-negative
bacterium in hospital-acquired infections. It causes death in many burn victims, cystic-…

Antibacterial activity of flavonoid isolated from Trianthema decandra against Pseudomonas aeruginosa and molecular docking study of FabZ

R Geethalakshmi, JC Sundaramurthi… - Microbial pathogenesis, 2018 - Elsevier
… The molecular docking of the flavonoid isolated from T. decandra was carried out using …
aeruginosa pathogen. The molecular docking studies indicate that the isolated compound has …

Molecular docking, and anti-biofilm activity of gold-complexed sulfonamides on Pseudomonas aeruginosa

CR Mizdal, ST Stefanello, PA Nogara, FAA Soares… - Microbial …, 2018 - Elsevier
aeruginosa. Besides, the compounds were also analyzed for the binding affinity through
molecular docking with LasR, a system regulator QS in P. aeruginosa [7]. …

In vivo, in vitro and molecular docking studies reveal the anti-virulence property of hispidulin against Pseudomonas aeruginosa through the modulation of quorum …

VT Anju, S Busi, MS Mohan, S Ranganathan… - International …, 2022 - Elsevier
… Anti-virulent and anti-biofilm efficacy of hispidulin against Pseudomonas aeruginosa PAO1
was explored in the current work by in vitro, in silico, and nematode infection model. The …

… Docking and Molecular Dynamics Studies to Identify Potential OXA-10 Extended Spectrum β-Lactamase Non-hydrolysing Inhibitors for Pseudomonas aeruginosa

K Malathi, S Ramaiah - Cell biochemistry and biophysics, 2016 - Springer
… -hydrolysing inhibitors for P. aeruginosa, it is necessary to understand the mechanism of
resistance at the structural level. We have performed molecular docking using imipenem as a …

Molecular docking and biological evaluation of novel urea-tailed mannich base against Pseudomonas aeruginosa

SK Mohanvel, V Ravichandran, C Kamalanathan… - Microbial …, 2019 - Elsevier
… Initially, the Mannich bases was examined for its ability to interact with the active sites of
LasR by molecular docking simulations. For LasR docking, N-(3-oxododecanoyl) l-homoserine …

Quorum Sensing Inhibitory Potential and Molecular Docking Studies of Phyllanthus emblica Phytochemicals Against Pseudomonas aeruginosa

S Baburam, S Ramasamy, G Shanmugam… - Applied Biochemistry …, 2022 - Springer
molecules known as N-acyl homoserine lactones (AHLs). In this present work, the anti-quorum
sensing activity of Phyllanthus emblica was evaluated against Pseudomonas aeruginosa. …

Molecular docking, quorum quenching effect, antibiofilm activity and safety profile of silver-complexed sulfonamide on Pseudomonas aeruginosa

FS Siqueira, CFS Alves, AK Machado, JD Siqueira… - Biofouling, 2021 - Taylor & Francis
… Therefore, in this study, Pseudomonas aeruginosa, an opportunistic Gram-negative bacterium
often associated with nosocomial infections related to biofilms, was selected. The QS in …

3D-QSAR, Molecular Docking and Molecular Dynamics Simulation of Pseudomonas aeruginosa LpxC Inhibitors

K Zuo, L Liang, W Du, X Sun, W Liu, X Gou… - … Journal of Molecular …, 2017 - mdpi.com
… using comparative molecular field analysis and comparative molecular similarity index …
Pseudomonas aeruginosa LpxC (PaLpxC) is revealed at the molecular level via molecular

… proteins involved in biofilm formation of Pseudomonas aeruginosa are prospective targets for natural lead molecules: Computational modelling, molecular docking …

S Skariyachan, R Ravishankar, D Gopal… - Infection, Genetics and …, 2020 - Elsevier
… selected lead molecules against GacA and RhlR were predicted by molecular docking and
… The stabilities of best docked complex were studied by molecular dynamic (MD) simulation. …