… The moleculardocking of the flavonoid isolated from T. decandra was carried out using … aeruginosa pathogen. The moleculardocking studies indicate that the isolated compound has …
… aeruginosa. Besides, the compounds were also analyzed for the binding affinity through moleculardocking with LasR, a system regulator QS in P. aeruginosa [7]. …
VT Anju, S Busi, MS Mohan, S Ranganathan… - International …, 2022 - Elsevier
… Anti-virulent and anti-biofilm efficacy of hispidulin against Pseudomonasaeruginosa PAO1 was explored in the current work by in vitro, in silico, and nematode infection model. The …
K Malathi, S Ramaiah - Cell biochemistry and biophysics, 2016 - Springer
… -hydrolysing inhibitors for P. aeruginosa, it is necessary to understand the mechanism of resistance at the structural level. We have performed moleculardocking using imipenem as a …
… Initially, the Mannich bases was examined for its ability to interact with the active sites of LasR by moleculardocking simulations. For LasR docking, N-(3-oxododecanoyl) l-homoserine …
S Baburam, S Ramasamy, G Shanmugam… - Applied Biochemistry …, 2022 - Springer
… molecules known as N-acyl homoserine lactones (AHLs). In this present work, the anti-quorum sensing activity of Phyllanthus emblica was evaluated against Pseudomonasaeruginosa. …
FS Siqueira, CFS Alves, AK Machado, JD Siqueira… - Biofouling, 2021 - Taylor & Francis
… Therefore, in this study, Pseudomonasaeruginosa, an opportunistic Gram-negative bacterium often associated with nosocomial infections related to biofilms, was selected. The QS in …
K Zuo, L Liang, W Du, X Sun, W Liu, X Gou… - … Journal of Molecular …, 2017 - mdpi.com
… using comparative molecular field analysis and comparative molecular similarity index … Pseudomonasaeruginosa LpxC (PaLpxC) is revealed at the molecular level via molecular …
S Skariyachan, R Ravishankar, D Gopal… - Infection, Genetics and …, 2020 - Elsevier
… selected lead molecules against GacA and RhlR were predicted by moleculardocking and … The stabilities of best docked complex were studied by molecular dynamic (MD) simulation. …