… mapping, we explore the footprint of target classes across disease areas and investigate the
success of privileged target … We also compile a list of drug target orthologues for standard …

… Genome-scale CRISPR knockout screens can discover many novel and medically important
drug targets [1], but it is predicted that traditional small-molecule drugs may not be used to …

… Molecular feature sets were consolidated on a human protein interaction network and
interpreted on the level of molecular … context defined as associated biomarkers and drug targets. …

… to provide new insight into drug repurposing molecular events involved in SARS–CoV–2.
We constructed three drug–target–pathways–disease networks to predict the targets and drugs …

… drug targets to inhibit mTOR by disrupting the complexation of the components with peptides
and small molecules… and the prospective drug targets that destabilize mTOR complexes. …

… tool PharmMapper for potential drug target prediction against any given small molecules
via a ‘reverse’ pharmacophore mapping approach. The small molecule might be a biologically …

… to broadly map … molecular aberrations and to identify new targets for therapy. In this study
we used the RPMA global pathway mapping technique in pediatric BCP-ALL patients to map …

… To identify potential drug targets for the AR metabolites, we … drug molecules available in
the DrugBank database 34 . The similarity index, namely the Tc between drug molecules and …

… In order to identify the efficacy targets — the molecular targets through which the drug …
The recent work on large-scale mapping of polypharmacology interactions reveals the extent of …

… GPCRs represent one of the most important families of drug targets for the pharmaceutical …
prominent classes of validated drug targets, is important for modern drug discovery. There are …