The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
molecular mechanisms is lacking. Recent studies demonstrate a positive feedback loop …
cytokine release and cell death pathways; certain cytokines, pathogen-associated molecular

… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… and dysfunctional cytokines response as some cytokines are … light on the molecular
mechanisms of the cytokines and their … to control and treat the cytokine storm or hypercytokinemia …

Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… If the inflammatory reaction is very pronounced, an ultimately uncontrolled release of
proinflammatory cytokines leads to cytokine storm with the known potentially lethal courses [168]. …

Modeling and simulations of CoViD-19 molecular mechanism induced by cytokines storm during SARS-CoV2 infection

Z Yu, R Ellahi, A Nutini, A Sohail, SM Sait - Journal of molecular liquids, 2021 - Elsevier
… Different computational models based on the molecular mechanism of the said problems,
are available in the literature [[14], [15], [16], [17]]. During this research, we developed a model …

Highways to hell: Mechanism-based management of cytokine storm syndromes

SW Canna, RQ Cron - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
… these mechanisms interact and overlap. Likewise, the utility of a broad term such as “cytokine
storm” is … CSS research must improve our appreciation of its various mechanisms and their …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… Pieces of evidence from current studies have shown that the cytokine storm may be an …
profile, the molecular mechanisms of the SARS-CoV-2-induced cytokine storm and immune …

The advent of the cytokine storm

IA Clark - Immunology and cell biology, 2007 - search.proquest.com
… The first use of cytokine storm to describe the mechanism of an infectious disease was …
Although cytokine storm can be a useful lay term, we must expect clinical and pathological …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - … and molecular …, 2012 - Am Soc Microbiol
… potential cellular and molecular mechanisms contributing to the cytokine storm in viral disease
(66… In this review, we focus on the cytokine storm in the context of infection, with particular …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… Furthermore, cytokine storm can cause post-COVID-19 … mechanisms involved in
COVID-19-related cytokine storm and its … targets to control cytokine storm wishing to answer unmet …

A new investigation into the molecular mechanism of andrographolide towards reducing cytokine storm

A Alzahrani - Molecules, 2022 - mdpi.com
… be exploited as therapeutics to reduce cytokine storm, the drug development … cytokines
that are secreted as a result of cytokine storm. We used molecular docking analyses, molecular