… D supplementation reduces the risk of the cytokine storm. However, the underlying molecular
mechanism of Vitamin D in suppressing the cytokine storm and reducing viral infection in …

… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

… about the real molecular mechanism of activity of tocilizumab. … IL-6) and can inhibit both
classical and trans signaling pathway (Figure 1). Though the underlying molecular mechanism of …

… The exaggerated cytokine release in response to viral infection, a condition known … cytokine
release syndrome (CRS) (Fig. 1) or cytokine storm, is emerging as one of the mechanisms …

… has been associated with a cytokine storm (CS) syndrome in … CoV were also characterized
by a cytokine storm [6]. There are … the duality of the cytokine storm phenomenon in COVID-19, …

… being elucidated, the term cytokine storm has become synonymous with … cytokine storm as
their rationale (NCT04306705, NCT04322773). A critical evaluation of the term cytokine storm …

… of cytokine storm: it does not specify precisely which cytokines must have elevated … cytokines
must be to constitute a cytokine storm. We would also like to include specific cytokines and …

… One of the worst scenarios is sustained by the so-called cytokine storm, historically labelled
… in triggering the cytokine storm. This cytokine storm may provide the possible mechanism on …

… Therefore, clarification of the molecular mechanism for how CRS promotes multiple symptoms
in coronavirus-related diseases is needed. Better understanding of this issue will facilitate …

… cytokine, chemokine, alarmins and inducible enzymes, which paves the pathway for cytokine
storm… -talk of NF-κB with regard to cytokine storm in COVID-19. Moreover, the development …