Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action

S Patra, B Pradhan, R Nayak, C Behera, S Das… - Phytomedicine, 2021 - Elsevier
impact on the drug efficacy for translation to clinical perspective. Hence, understanding the
molecular mechanisms of action of … , their molecular targets, mode of action, preclinical and …

Sulforaphane as an anticancer molecule: Mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems

MM Kamal, S Akter, CN Lin, S Nazzal - Archives of pharmacal research, 2020 - Springer
… and synergistic effects. Although a good number of reviews have reported on the mechanisms
… activity, a comprehensive review on the synergistic effect of sulforaphane and its delivery …

Molecular mechanisms of action of BPA

F Acconcia, V Pallottini, M Marino - Dose-response, 2015 - journals.sagepub.com
… In addition, the large number of endocrine-disrupting compounds present in the environment
raises questions about the possible additive, synergic effects of simultaneous exposure to …

Synergistic action of pro-inflammatory agents: cellular and molecular aspects

SR Paludan - Journal of leukocyte biology, 2000 - academic.oup.com
… In addition, these components synergistically induce secretion of tumor necrosis factor …
The molecular mechanisms underlying the synergistic gene induction discussed in this review …

Synergistic therapeutic actions of herbal ingredients and their mechanisms from molecular interaction and network perspectives

XH Ma, CJ Zheng, LY Han, B Xie, J Jia, ZW Cao… - Drug discovery today, 2009 - Elsevier
… , there are other varieties of mechanisms for enhancing or … synergistic actions and other
molecular mechanisms of herbal ingredients, it is important to take into consideration the effects

Mechanism of action of proteasome inhibitors and deacetylase inhibitors and the biological basis of synergy in multiple myeloma

T Hideshima, PG Richardson, KC Anderson - Molecular cancer therapeutics, 2011 - AACR
… The mechanistic basis of synergy is … of the mechanism of action of proteasome inhibitors
and DACi in multiple myeloma and examines the biological basis of their synergistic effects. …

Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action

S Wang, Q Liu, Y Zhang, K Liu, P Yu, K Liu, J Luan… - Molecular Cancer, 2009 - Springer
… BER shows synergistic effects with some existing anticancer agents such as trichostatin
A (… BER also has synergistic effects with anticancer agents trichostatin A, celecoxib and/or …

[HTML][HTML] Molecular mechanism of action and potential biomarkers of growth inhibition of synergistic combination of afatinib and dasatinib against gefitinib-resistant non …

M Wang, AYC Chang - Oncotarget, 2018 - ncbi.nlm.nih.gov
… of advanced NSCLC from synergistic interactions and avoidance … the potential biomarkers
predicating synergism of the combination. … and uncovered the molecular mechanism of tumour …

The Molecular Mechanisms of Apoptosis Induced by Allium flavum L. and Synergistic Effects with New‐Synthesized Pd(II) Complex on Colon Cancer Cells

M Milutinović, M Stanković, D Cvetković… - Journal of food …, 2015 - Wiley Online Library
… concerning molecular mechanisms of … synergistic effects of A. flavum extracts and Pd(II)
complex. The main objective was to investigate proapoptotic effects and molecular mechanisms

Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate …

E Giovannetti, C Lemos, C Tekle, K Smid… - Molecular …, 2008 - ASPET
… This study investigated molecular mechanisms underlying their combination in six NSCLC
cell lines. Cells were characterized by heterogeneous expression of pemetrexed determinants…