Molecular networks that regulate cancer metastasis

D Spano, C Heck, P De Antonellis, G Christofori… - Seminars in cancer …, 2012 - Elsevier
… functional networks of molecules contribute to the development of … provide the basis for the
development of new aspects in the … inhibition of these proteins and their molecular networks. …

Molecular networks in Network Medicine: Development and applications

EK Silverman, HHHW Schmidt… - … Systems Biology and …, 2020 - Wiley Online Library
molecular data that are used in molecular network analyses, survey the analytical methods
for inferring molecular networks… of molecular data that are used in molecular network analyses…

Molecular networks of FOXP family: dual biologic functions, interplay with other molecules and clinical implications in cancer progression

JH Kim, J Hwang, JH Jung, HJ Lee, DY Lee, SH Kim - Molecular cancer, 2019 - Springer
development, immune disorders and cancermolecular networks with other proteins and
noncoding RNAs, cellular immunotherapy targeting FOXP3, and clinical implications in cancer

Trastuzumab and beyond: sequencing cancer genomes and predicting molecular networks

DH Roukos - The pharmacogenomics journal, 2011 - nature.com
… into molecular mechanisms underlying cancer development and metastasis will emerge.
However, the distance from this general and imprecise statement to reach clinical success with …

Understanding biological functions through molecular networks

JDJ Han - Cell research, 2008 - nature.com
… mapping of molecular networks have allowed us to study biology from the network
perspective. … With the development of ready-to-use network analysis and modeling tools the …

Cancer systems biology: a network modeling perspective

PK Kreeger, DA Lauffenburger - Carcinogenesis, 2010 - academic.oup.com
… To model this process, one approach has been to develop mass-action models that
decompose the intrinsic apoptotic pathway into subsections of the molecular network for analysis ( …

Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma

KM Sheehan, VS Calvert, EW Kay, Y Lu… - Molecular & Cellular …, 2005 - ASBMB
Cancer can be defined as a deregulation or hyperactivity in the ongoing network of intracellular
… Thus, in addition to elucidation of the molecular network within a tumor specimen, critical …

Molecular signaling network complexity is correlated with cancer patient survivability

D Breitkreutz, L Hlatky, E Rietman… - Proceedings of the …, 2012 - National Acad Sciences
… role in the development and progression of cancer (29); however, BioCyc does not
associate this signaling pathway with a specific cancer site (such as lung or pancreatic cancer). …

Integration of multiomics data with graph convolutional networks to identify new cancer genes and their associated molecular mechanisms

R Schulte-Sasse, S Budach, D Hnisz… - Nature Machine …, 2021 - nature.com
… Cell-adhesion molecules take part in the intercellular and extracellular matrix interactions
of cancer, playing a pivotal role in cancer development and metastasis 55 . The first big SCC …

Robustness and lethality in multilayer biological molecular networks

X Liu, E Maiorino, A Halu, K Glass, RB Prasad… - Nature …, 2020 - nature.com
… The second set is composed of the genes that have been causally implicated in cancer
development, integrated from the Cancer Gene Census 57 . We note that, while a number of …