[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
molecular mechanisms is lacking. Recent studies demonstrate a positive feedback loop …
cytokine release and cell death pathways; certain cytokines, pathogen-associated molecular

[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… levels of pro-inflammatory cytokines are produced during the crosstalk between epithelial
cells and immune cells in COVID-19, which has linked the cytokine storm (CS) with the severe …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… Here, in the following sections, we provide an overview of substantial inflammatory cytokines
and pathways implicated in the pathogenesis of COVID-19-associated cytokine storm. IL-6

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… Therefore, using strategies to effectively suppress cytokine storm is essential for … cytokine
storm is induced by the virus will be introduced in detail, including the ways in which cytokines

[HTML][HTML] Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - … journal of molecular …, 2021 - mdpi.com
… mechanisms underlying cytokine storm induction and … cytokine storms are described from
both host and pathogen perspectives. In summary, current studies indicate that cytokine storm-…

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - … and molecular …, 2012 - Am Soc Microbiol
… a cytokine storm and the biological consequences of cytokine overproduction. We will also
look at the cytokine storm … the importance of the kinetics of cytokine gene expression and the …

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
… We addressed the specific signaling events that can cause cytokine storm and demonstrated
three forms of cell death signaling following virus infection, including apoptosis, pyroptosis, …

[HTML][HTML] The potential role of cytokine storm pathway in the clinical course of viral respiratory pandemic

G Murdaca, F Paladin, A Tonacci, S Isola, A Allegra… - Biomedicines, 2021 - mdpi.com
… It is in this context that the “cytokine storm” syndrome … the potential role of the cytokine storm
during the clinical course of … the importance of the cytokine storm during the infection of these …

[HTML][HTML] … cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… Different molecular pathways, such as the activation of JAK and JAK/STAT signaling … of
cytokine storm; hence, various mechanisms, immunological pathways, and functions of cytokines

[HTML][HTML] Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
cytokine release, delayed neutrophil apoptosis, and NETosis contribute to pulmonary
thrombosis and cytokine storm… high expression of inflammatory cytokines on the TNF-α/IL-6 axis, …