The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… suggested that cytokine storm correlated … a cytokine storm remains limited. In this review,
we focus on the potential mechanisms responsible for severe influenza-induced cytokine storm

Modeling and simulations of CoViD-19 molecular mechanism induced by cytokines storm during SARS-CoV2 infection

Z Yu, R Ellahi, A Nutini, A Sohail, SM Sait - Journal of molecular liquids, 2021 - Elsevier
… An overproduction of proinflammatory cytokines, however, can give rise to what is called
a “cytokine storm” which can have a harmful effect on the body through the production of a …

Tocilizumab: a therapeutic option for the treatment of cytokine storm syndrome in COVID-19

A Saha, AR Sharma, M Bhattacharya, G Sharma… - Archives of medical …, 2020 - Elsevier
IL-6 plays an important role in inducing this cytokine storm (both by its classical and trans
signaling pathway) … , some molecules should be present or applied to block both of its signaling …

Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
… Another way to restrain the excessive level of cytokine signalling or cytokine storm is the
use of Janus kinase inhibitors (JAKi).Most JAK inhibitors are specifically effective at JAK1 and …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

[图书][B] What is “Cytokine Storm”? Understanding its Role in the Pathology of Clinical & Infectious Disease at Molecular Level.

HK Saboowala - 2020 - books.google.com
… and molecular mechanisms contributing to the cytokine storm in … Thus, it would be worth to
focus on the cytokine storm in the … methods are revealing new insights into the cytokine storm. …

The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
… a cytokine storm in critical patients with COVID-19. Therefore, effectively suppressing the
cytokine storm … infection induces cytokine storm and the options to inhibit the cytokine storm, in …

[HTML][HTML] Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms

S Kang, T Kishimoto - Experimental & molecular medicine, 2021 - nature.com
… contributions of IL-6 signaling to the pathogenesis of several types of cytokine storms and
discuss potential therapeutic strategies for the management of cytokine storms, including those …

[HTML][HTML] How COVID-19 induces cytokine storm with high mortality

S Hojyo, M Uchida, K Tanaka, R Hasebe… - Inflammation and …, 2020 - Springer
… that IL-6 inhibitors including TCZ could mitigate cytokine stormsIL-6 inhibitors could
suppress cytokine storms in patients after CAR-T cell therapy most likely did so by blocking the IL-6

[HTML][HTML] A network-based analysis reveals the mechanism underlying vitamin D in suppressing cytokine storm and virus in SARS-CoV-2 infection

F Ahmed - Frontiers in immunology, 2020 - frontiersin.org
… the pathways associated with cytokine storm in SARS-CoV-2 infection. The proposed
underlying mechanism of Vitamin D could be promising in suppressing the cytokine storm and …