Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
… The exaggerated cytokine release in response to viral infection, a condition known as
cytokine release syndrome (CRS) or cytokine storm, is emerging as the mechanism leading to …

[HTML][HTML] Intricate relationship between SARS-CoV-2–induced shedding and cytokine storm generation: A signaling inflammatory pathway augmenting COVID-19

MB Moftah, A Eswayah - Health Sciences Review, 2022 - Elsevier
… Another prominent contributor to this storm in patients with … in the pathogenesis of the cytokine
storm related to COVID-19 … to understanding the signaling pathways that are implicated in …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… by elevated levels of pro-inflammatory cytokines, referred to as cytokine storm. Interleukins,
such as … Cytokine storm is defined as acute overproduction and uncontrolled release of pro-…

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
… -based review of the associated pathways and potential treatment of the … to as cytokine
storm in its severest form has been marked by elevation of IL-6, IL-10, TNF-α, and other cytokines

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
… vaccine; anti-cytokine therapy such as IL-6, TNFα and IL… pathways of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and its relationship with the host cytokine storm

Cytokine storm and signaling pathways: pathogenesis of SARS‐CoV‐2 infection, managing and treatment strategies

R Kumar, K Gulia - 2021 - wlv.openrepository.com
cytokine storm possibly exist (Figure 1). Furthermore, there is a need to develop a blueprint
of molecular mechanism underlying the cytokine storm … prevent a cytokine storm or suppress …

Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
… have reported that cytokine storms are an … how cytokine storms promote the deterioration
of COVID-19. Here, we outline the pathophysiological processes through which cytokine storms

VISTA: a target to manage the innate cytokine storm

MA ElTanbouly, Y Zhao, E Schaafsma… - Frontiers in …, 2021 - frontiersin.org
… of cytokine storms which occur in viral infections, inflammatory diseases and allogeneic
responses, monocytes and macrophages are the major producers of inflammatory cytokines that …

The mechanism behind influenza virus cytokine storm

Y Gu, X Zuo, S Zhang, Z Ouyang, S Jiang, F Wang… - Viruses, 2021 - mdpi.com
… the immune mechanisms and pathways behind cytokines in the cytokine storm induced
by the influenza virus. We also examined the differences of cytokine storms in different ages, …

Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents

S Khadke, N Ahmed, N Ahmed, R Ratts, S Raju… - Virology journal, 2020 - Springer
… Some patients further progress to phase 3 characterized by cytokine storm with worsening
respiratory symptoms, persistent fever, and hemodynamic instability. Important cytokines