Phase 2/3 trial of molnupiravir for treatment of Covid-19 in nonhospitalized adults

Y Caraco, GE Crofoot, PA Moncada… - NEJM …, 2022 - evidence.nejm.org
… dose-limiting in this small sample of nonhospitalized adults with Covid-19. The … molnupiravir,
when initiated early in the course of illness, is an effective option for the treatment of adults

[HTML][HTML] Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … England Journal of …, 2022 - Mass Medical Soc
… of treatment with molnupiravir started within 5 days after the onset of signs or symptoms in
nonhospitalized, unvaccinated adults … to receive 800 mg of molnupiravir or placebo twice daily …

Effectiveness of nirmatrelvir/ritonavir and molnupiravir in non-hospitalized adults with COVID-19: systematic review and meta-analysis of observational studies

YM Mesfin, JE Blais, KT Kibret… - Journal of …, 2024 - academic.oup.com
non-hospitalized adults and assessed treatment initiation with nirmatrelvir/ritonavir or
molnupiravir versus no antiviral treat… and/or molnupiravir were the intervention with the treatment

Efficacy and safety of molnupiravir for the treatment of non-hospitalized adults with mild COVID-19: a randomized, open-label, parallel-group phase 3 trial

SK Tippabhotla, DS Lahiri, C Kandi - 2022 - papers.ssrn.com
… , is being repurposed for the treatment of COVID-19. This study evaluates the efficacy
and … of molnupiravir in addition to the standard-of-care (SOC) for the treatment of non-hospitalized

Clinical efficacy and safety of molnupiravir for nonhospitalized and hospitalized patients with COVID‐19: A systematic review and meta‐analysis of randomized control …

PY Huang, TH Liu, JY Wu, YW Tsai… - Journal of Medical …, 2023 - Wiley Online Library
… These findings support the recommended use of molnupiravir for treating nonhospitalized
… and November 2021 Nonhospitalized adults with COVID-19 within 5 days of symptom onset …

[HTML][HTML] Current status of oral antiviral drug treatments for SARS-CoV-2 infection in non-hospitalized patients

DV Parums - … science monitor: international medical journal of …, 2022 - ncbi.nlm.nih.gov
… significantly reduced the risk of hospitalization or death in adults … of molnupiravir given
within five days after the onset of signs or symptoms in unvaccinated and non-hospitalized adults

COVID-19 therapeutics for nonhospitalized patients

RT Gandhi, PN Malani, C Del Rio - Jama, 2022 - jamanetwork.com
… theoretical concerns that molnupiravir may cause mutations in … Authorization for molnupiravir
for treatment of adults with mild … Molnupiravir is not recommended during pregnancy and is …

[HTML][HTML] Real-world clinical outcomes of molnupiravir for the treatment of mild to moderate COVID-19 in adult patients during the dominance of the omicron variant: A …

C Huang, TL Lu, L Lin - Antibiotics, 2023 - mdpi.com
… had no benefit for hospitalized patients and showed a decreased mortality risk for non-hospitalized
patients when compared to placebo [32]. This brief meta-analysis included two …

Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling …

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - The Lancet, 2022 - thelancet.com
… including molnupiravir and nirmatrelvir plus ritonavir are novel options for treating adults
with COVID-19 received molnupiravir or nirmatrelvir plus ritonavir treatment in the outpatient …

COVID-19 treatments approved in the European Union and clinical recommendations for the management of non-hospitalized and hospitalized patients

S Bellino - Annals of medicine, 2022 - Taylor & Francis
… early use of molnupiravir (Lagevrio) before marketing authorization, under Article 5(3) of
Regulation 726/2004. Molnupiravir can be used for the treatment of COVID-19 in adults who do …