Real-world experience with molnupiravir during the period of SARS-CoV-2 Omicron variant dominance

R Flisiak, D Zarębska-Michaluk, M Rogalska… - Pharmacological …, 2022 - Springer
… It was the phase 2/3 MOVe-OUT clinical trial in non-hospitalized … The present study included
590 adult patients from 13 centers, … treated with molnupiravir (MOL) or without any antiviral …

A retrospective real-world study of early short-course remdesivir in non-hospitalized COVID-19 patients at high risk for progression: low rate of hospitalization or death …

JM Ramos-Rincón, H Pinargote-Celorio… - Frontiers in …, 2023 - frontiersin.org
… We included adult patients with mild-to-moderate SARS-CoV-2 infection (confirmed by RT-PCR)
at high risk for disease progression, who were treated as outpatients with a 3-day …

Nirmatrelvir–ritonavir for the treatment of COVID‐19 patients: A systematic review and meta‐analysis.

HA Cheema, U Jafar, A Sohail… - Journal of Medical …, 2023 - search.ebscohost.com
molnupiravir and nirmatrelvir–ritonavir are both oral drugs, there have been concerns about
teratogenicity and mutagenicity with molnupiravir.… ‐risk, nonhospitalized adults with Covid‐19…

[HTML][HTML] Rebound COVID-19 and cessation of antiviral treatment for SARS-CoV-2 with Paxlovid and molnupiravir

DV Parums - … Science Monitor: International Medical Journal of …, 2022 - ncbi.nlm.nih.gov
Molnupiravir was based on a phase 3 trial on the efficacy and safety of molnupiravir
treatment … or symptoms of COVID-19 in nonhospitalized, unvaccinated adults with mild-to-moderate …

Molnupiravir, nirmatrelvir/ritonavir, or sotrovimab for high-risk COVID-19 patients infected by the omicron variant: hospitalization, mortality, and time until negative …

L Cegolon, R Pol, O Simonetti, F Larese Filon… - Pharmaceuticals, 2023 - mdpi.com
… 7,013 non-hospitalized adult COVID-19 patients infected between 16 December 2021 and
22 April 2022—4973 controls against 2040 patients treated either with Molnupiravir (N = 3591…

Lopinavir/ritonavir for treatment of non-hospitalized patients with COVID-19: a randomized clinical trial

AM Kaizer, NI Shapiro, J Wild, SM Brown… - International Journal of …, 2023 - Elsevier
… This randomized, placebo (Plb)-controlled, double-blind, multi-site decentralized clinical
trial enrolled non-hospitalized adults with confirmed SARS-CoV-2 infection and six or fewer …

Effect of pre-hospitalization use of oral antiviral agents on reducing critical illness and mortality for patients with COVID-19 pneumonia

YC Yii, HM Shih, CL Chen, ZL Lai, YL Hsu… - International Journal of …, 2024 - Elsevier
… nirmatrelvir/ritonavir and molnupiravir before hospitalisation on subsequent … molnupiravir
are effective in reducing hospitalisation and mortality rates in the setting of outpatient treatment

[HTML][HTML] Molnupiravir—a step toward orally bioavailable therapies for Covid-19

R Whitley - New England Journal of Medicine, 2022 - Mass Medical Soc
… Development (EIDD), molnupiravir is active against influenza … EIDD developed molnupiravir
for the treatment of pathogenic … 2–3 placebo-controlled trial of molnupiravir that may begin to …

[HTML][HTML] The pill of recovery; Molnupiravir for treatment of COVID-19 patients; a systematic review

L Kamal, A Ramadan, S Farraj, L Bahig… - Saudi Pharmaceutical …, 2022 - Elsevier
… proof that oral Molnupiravir is effective for the treatment of … non-hospitalized unvaccinated
adults, the FDA and NIH COVID-19 treatment guideline both recommended using Molnupiravir

Molnupiravir as an early treatment for COVID-19: a real life study

M Pontolillo, C Ucciferri, P Borrelli, M Di Nicola… - Pathogens, 2022 - mdpi.com
… use of molnupiravir, the first antiviral drug against SARS-CoV-2 available to us, in the treatment
of … All patients received molnupiravir (800 mg twice daily). Blood chemistry checks were …