… cytokine patterns, it seems that the cytokine storm plays a crucial role in the pathogenesis of
COVID-19-, SARS- and MERS. Monocytes and macrophages … monocytes and macrophages. …

… Although the increased systemic cytokine response in COVID-19 is undisputed, the term “cytokine
storm” in COVID-19 pathophysiology is a topic of debate, as TNF, IL-6, and IL-8 …

… Monocytes and macrophages as the most important cells of … in their function such as cytokine
storm can be so harmful to the … During the infection, monocytes and macrophages may be …

… CD14 + CD16 + monocytes are mediated by membrane-bound … This is followed by the
infiltration of macrophages and … + inflammatory monocytes to produce large quantities of IL-6, …

… , neutrophilia, dysregulation of monocytes and macrophages, reduced or … , cytokine storm
(CS). The CS is characterized by hyperproduction of an array of pro-inflammatory cytokines …

… monocytes and macrophages, given that a reduced response from T lymphocytes triggers an
uncontrolled cytokine release and cytokine storm … Interestingly, macrophages infected with …

… Monocyte depletion or therapeutic depletion of IL-6 and IL-1 … of macrophages at disease
onset was shown to decrease lethality and limit the cytokine storm, pointing to macrophage-…

… found inflammatory monocyte‐derived FCN1 + macrophages in … monocytes secreting MCP1,
IP‐10 and macrophage inflammatory protein‐1α (MIP‐1α) contributing to the cytokine storm …

… in lungs and explore the potential function of monocytes/macrophages in response to SARS-…
monocytes/macrophages and highlighted the role of the aberrantly activated macrophages …

… that human monocytes were the major source of IL-1 and IL-6 … found that both
monocyte depletion and blocking IL-6 or IL-1 … All of these findings suggest that monocytes/macrophages …