[HTML][HTML] The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
… of large amounts of pro-inflammatory cytokines. The cytokine storm in COVID-19 can mimic
… The purpose of this review is to emphasize the importance of the cytokine storm situation …

[HTML][HTML] Cytokine storm intervention in the early stages of COVID-19 pneumonia

X Sun, T Wang, D Cai, Z Hu, H Liao, L Zhi, H Wei… - Cytokine & growth factor …, 2020 - Elsevier
cytokine storm observed in COVID-19 illness is also an important component of mortality in
… In view of the severe morbidity and mortality of COVID-19 pneumonia, we review the current …

[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… and are at risk for increased mortality and morbidity. Common pathogens are encapsulated
… are by far the most common cause of being associated with a mortality rate of up to 60% [96]. …

[HTML][HTML] Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
cytokine and chemokine levels with morbidity and mortality … quell the pathology associated
with cytokine storm. In fact, the … postulate whether robust cytokine and chemokine production …

Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate …

MBA Oldstone, H Rosen - … -1-Phosphate Signaling in Immunology and …, 2014 - Springer
… result of cytokine storm. This chapter visits primarily influenza virus infection and resultant
cytokine storm. It provides the compelling evidence that illuminates cytokine storm in influenza …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
… The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

[HTML][HTML] Hazards of the cytokine storm and cytokine-targeted therapy in patients with COVID-19

M Quirch, J Lee, S Rehman - Journal of medical Internet research, 2020 - jmir.org
… Current research indicates that cytokine storm is one of the leading causes of morbidity and
mortality in patients with COVID-19. This evidence is based on elevated levels of interleukins …

The cytokine storm and factors determining the sequence and severity of organ dysfunction in multiple organ dysfunction syndrome

H Wang, S Ma - The American journal of emergency medicine, 2008 - Elsevier
… Multiple organ dysfunction syndrome (MODS) is a major cause of morbidity and mortality
in intensive care units. It is being encountered frequently in critically ill patients owing to …

Cytokine release syndrome in COVID-19: a major mechanism of morbidity and mortality

Y Que, C Hu, K Wan, P Hu, R Wang, J Luo… - International reviews …, 2022 - Taylor & Francis
… Ultimately, there is great promise that an anti-inflammatory modulator targeting a cytokine
storm effect may prove to be very beneficial in reducing morbidity and mortality in COVID-19 …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
morbidity and mortality have been attributed to a pathologic host response. Two divergent
hypotheses have been proposed: hyperinflammatory cytokine storm; … had increased IL-6 levels …