… and in those deficient in chromatin-modifying enzymes … mouse germ cells as well as the
outstanding questions relating to the regulation of the dynamic chromatin landscape in germ cells…

… To compare PMSC features with gene expression profiles, we next re-analyzed RNASeq
datasets performed on purified mouse germ cells at different stages of spermatogenesis (…

… Here, we show that most promoters in mouse sperm are flanked by well-positioned …
DNA methylation is erased, although not completely, and re-established during germ cell …

… To further reveal TFs that drive the germ cell development, we pruned the data by correlating
gene expression of a TF to its corresponding TF z- score (Figure 4—figure supplement 2A …

… Although the genome-wide histone modification landscapes of mouse in vivo germ cells
and in vitro PGCLCs have been profiled and several germline-specific properties of epigenetic …

… Mapping accessible chromatin in mouse and human PGCs To obtain a comprehensive
landscape of the accessible chromatin in mouse and human PGCs, we developed a low-input …

… DNA methylation reprogramming is important for germ cell development and … of mouse
primordial germ cell (PGC)-like cells, produced from embryonic stemcell-derived epiblast-like cells…

… The transcriptional landscapes of human FGC development … chromatin state of these genomic
elements during germ cell … Combined with these results in human and in mice, we propose …

… transcription in differentiated cells and cancer 1 . The developing mouse germ line endures
… This sex-specific effect of Ezh2 deletion is explained by the distinct landscape of repressive …

… Here, we profiled the chromatin … cells, and early- and late-stage hPGCLCs, respectively.
Collectively, our data characterized the chromatin accessibility and transcriptome landscapes …