[HTML][HTML] Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets

Z Miao, MS Balzer, Z Ma, H Liu, J Wu… - Nature …, 2021 - nature.com
… chromatin landscape of the developing and adult mouse kidneys … adult mouse kidneys at
single cell resolution, we performed single nuclei ATAC-seq (snATAC-seq) on kidneys of mice

Embryonic renal epithelia: induction, nephrogenesis, and cell differentiation

MF Horster, GS Braun, SM Huber - Physiological reviews, 1999 - journals.physiology.org
… ) kidney rudiments when removed at embryonic day 11 (E11) (mouse) follow an almost normal
developmental program … have shown that a mouse kidney cell line cultured on ECM forms …

Engineering kidney cells: reprogramming and directed differentiation to renal tissues

MM Kaminski, J Tosic, R Pichler, SJ Arnold… - Cell and Tissue …, 2017 - Springer
… in embryonic renal development of mice and directed differentiation protocols towards renal
cell fate… that single TFs can induce specific differentiation programmes such as the myogenic …

[HTML][HTML] A fork in the road of cell differentiation in the kidney tubule

Q Al-Awqati, GJ Schwartz - The Journal of clinical …, 2004 - Am Soc Clin Investig
cell and principal cell proteins, yet the acid/base transport function of the kidney was disrupted
and the mice exhibited distal renalmice, it is likely that Foxi1 activates a whole program of …

[HTML][HTML] Gene expression programs of mouse endothelial cells in kidney development and disease

EW Brunskill, SS Potter - PloS one, 2010 - journals.plos.org
renal disease. In this report we define the comprehensive gene expression programs of multiple
types of kidney … Tie2-GFP mice by cell dissociation and fluorescent activated cell sorting. …

[HTML][HTML] Acellular mouse kidney ECM can be used as a three-dimensional substrate to test the differentiation potential of embryonic stem cell derived renal progenitors

M Sambi, T Chow, J Whiteley, M Li, S Chua… - Stem Cell Reviews and …, 2017 - Springer
… properties of the adult kidney ECM in regards to supporting cell differentiation and survival.
… Organs respond to damage by initiating a repair program that involves cell proliferation, …

In vitro differentiation of murine embryonic stem cells toward a renal lineage

SJ Bruce, RW Rea, AL Steptoe, M Busslinger… - Differentiation, 2007 - Elsevier
… progenitor cell development and subsequent kidney … and/or direct contact with mouse
embryonic fibroblasts (MEFs… for activation of a kidney cell differentiation program. The WT1 gene is …

Temporal and spatial transcriptional programs in murine kidney development

G Challen, B Gardiner, G Caruana… - Physiological …, 2005 - journals.physiology.org
… the network associated with cellular differentiation (P < 2.9 × … dpc embryonic kidneys from
the Hoxb7/GFP transgenic mice, … of the kidney) cells using fluorescence-activated cell sorting. …

[PDF][PDF] Single-cell profiling reveals sex, lineage, and regional diversity in the mouse kidney

A Ransick, NO Lindström, J Liu, Q Zhu, JJ Guo… - Developmental cell, 2019 - cell.com
… -cell RNA sequencing of the adult male and female mouse kidney with in situ expression
studies and cell lineage … These studies reveal cell diversity and marked sex differences, distinct …

Single cell resolution regulatory landscape of the mouse kidney highlights cellular differentiation programs and renal disease targets

Z Miao, MS Balzer, Z Ma, H Liu, J Wu, R Shrestha… - bioRxiv, 2020 - biorxiv.org
mouse kidneys at single cell resolution, we performed single nuclei ATAC-seq (snATAC-seq)
on kidneys of mice … In parallel, we also performed bulk (whole kidney) ATAC-seq analysis …