… the mRNA-1273 SARS-CoV-2 vaccine encoding a stabilized prefusion spike trimer, S-2P. Experience with the mRNA platform for other candidate vaccines … clinical vaccine candidate in …
… need for improved mRNAvaccine formulations or the use of other types of vaccines. In this review, we discuss the advantages and limitations of mRNAvaccines targeting SARS-CoV-2 …
… Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNAvaccines are … vaccinated individuals have raised questions about the durability of immunity after vaccination…
… In conclusion, the SARS-CoV-2 mRNAvaccines were highly … Widespread vaccination can be expected to have a major … [ 29 , 30 ] While SARS-CoV-2 mRNAvaccines appear to provide …
… However, there remain significant challenges in the development and testing of vaccines as … of mRNA-based SARS-CoV-2 vaccines and the current status of the mRNA-1273 vaccine. …
JS Turner, JA O'Halloran, E Kalaidina, W Kim… - Nature, 2021 - nature.com
… In this study, we show SARS-CoV-2 mRNAvaccine-induced germinal centre B cells are maintained at or near peak frequencies for at least 12 weeks after secondary immunization. …
P Deepak, W Kim, MA Paley, M Yang… - Annals of internal …, 2021 - acpjournals.org
… to mRNA-based SARS-CoV-2 vaccination in immunosuppressed patients may be reduced. This study assessed the response to 2 doses of mRNA-based SARS-CoV-2 vaccine among …
… We conclude that the plasma neutralizing activity elicited by mRNAvaccination or natural … that are found in emerging variants of SARS-CoV-2. Vaccine-elicited monoclonal antibodies …
… mRNA-1273, an mRNAvaccine that encodes a SARS-CoV-2 spike protein that is stabilized in the prefusion conformation. Here we show that mRNA-… D614G mutant 2 SARS-CoV-2 as …