[HTML][HTML] SARS-CoV-2 mRNA vaccines: immunological mechanism and beyond

E Bettini, M Locci - Vaccines, 2021 - mdpi.com
… of the immune responses elicited by SARS-CoV-2 mRNA vaccines, built on the data from …
mRNA vaccine uptake/biodistribution and the innate immune response to mRNA vaccines are …

[HTML][HTML] An mRNA vaccine against SARS-CoV-2—preliminary report

LA Jackson, EJ Anderson, NG Rouphael… - New England journal …, 2020 - Mass Medical Soc
… the mRNA-1273 SARS-CoV-2 vaccine encoding a stabilized prefusion spike trimer, S-2P.
Experience with the mRNA platform for other candidate vaccines … clinical vaccine candidate in …

[HTML][HTML] mRNA vaccines against SARS-CoV-2: Advantages and caveats

M Echaide, L Chocarro de Erauso… - International Journal of …, 2023 - mdpi.com
… need for improved mRNA vaccine formulations or the use of other types of vaccines. In
this review, we discuss the advantages and limitations of mRNA vaccines targeting SARS-CoV-2 …

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

RR Goel, MM Painter, SA Apostolidis, D Mathew… - Science, 2021 - science.org
… Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are …
vaccinated individuals have raised questions about the durability of immunity after vaccination

[HTML][HTML] Effectiveness of SARS-CoV-2 mRNA vaccines for preventing Covid-19 hospitalizations in the United States

MW Tenforde, MM Patel, AA Ginde, DJ Douin… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… In conclusion, the SARS-CoV-2 mRNA vaccines were highly … Widespread vaccination can
be expected to have a major … [ 29 , 30 ] While SARS-CoV-2 mRNA vaccines appear to provide …

[HTML][HTML] An evidence based perspective on mRNA-SARS-CoV-2 vaccine development

F Wang, RM Kream, GB Stefano - Medical science monitor …, 2020 - ncbi.nlm.nih.gov
… However, there remain significant challenges in the development and testing of vaccines as
… of mRNA-based SARS-CoV-2 vaccines and the current status of the mRNA-1273 vaccine. …

[HTML][HTML] SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses

JS Turner, JA O'Halloran, E Kalaidina, W Kim… - Nature, 2021 - nature.com
… In this study, we show SARS-CoV-2 mRNA vaccine-induced germinal centre B cells are
maintained at or near peak frequencies for at least 12 weeks after secondary immunization. …

Effect of immunosuppression on the immunogenicity of mRNA vaccines to SARS-CoV-2: a prospective cohort study

P Deepak, W Kim, MA Paley, M Yang… - Annals of internal …, 2021 - acpjournals.org
… to mRNA-based SARS-CoV-2 vaccination in immunosuppressed patients may be reduced.
This study assessed the response to 2 doses of mRNA-based SARS-CoV-2 vaccine among …

[HTML][HTML] mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

Z Wang, F Schmidt, Y Weisblum, F Muecksch… - Nature, 2021 - nature.com
… We conclude that the plasma neutralizing activity elicited by mRNA vaccination or natural …
that are found in emerging variants of SARS-CoV-2. Vaccine-elicited monoclonal antibodies …

[HTML][HTML] SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

KS Corbett, DK Edwards, SR Leist, OM Abiona… - Nature, 2020 - nature.com
mRNA-1273, an mRNA vaccine that encodes a SARS-CoV-2 spike protein that is stabilized
in the prefusion conformation. Here we show that mRNA-… D614G mutant 2 SARS-CoV-2 as …