… Conclusions: Our results show a nonredundant and novel role of JAM-A in controlling
mucosal homeostasis by regulating the integrity and permeability of epithelial barrier function. …

… inflammation in health, inflammatory bowel disease (IBD), and the … of immune cells to the
gut mucosa, the expression of chemokine … of mucosal homeostasis and disease pathogenesis. …

… our understanding of the pathogenesis of chronic idiopathic inflammatory bowel diseases
(IBD), particularly Crohn's disease. Crohn's disease seems to be the result of an overly …

… Recent evidence indicates that mucosal barrier dysfunction … bowel disease (IBD). In this
review, we focus on the mechanisms by which mucosal barriers maintain gut homeostasis. …

… Intestinal macrophages are essential for local homeostasis and in keeping a balance …
targets for treatment of inflammatory bowel diseases such as Crohn’s disease. Until recently, the …

… of mucosal T cells to the numerous enteric antigens sampled by epithelial cells, contributing
to the maintenance of mucosal homeostasis … to the maintenance of mucosal homeostasis [5]. …

… Recent studies of intestinal mucosal homeostasis … mucosal homeostasis by maintaining
the balance between antipathogen immunity and commensal tolerance. Intestinal homeostasis …

… In summary, although it is clear that T H 17 cytokines are important in many aspects of
intestinal homeostasis and protection from mucosal pathogens, their role in IBD pathogenesis …

… IBD compared with the normal mucosa. Taken together, our results further support a role for
CXCL12 and its receptors in the intestinal mucosa in homeostasis and inflammation, thereby …

… SCFAs also mediate activation of STAT3 which plays a vital role in mucosal homeostasis[100,101].
Clostridia-related segmented filamentous bacteria promote IL-23 production by …