Mucosal immunity in COVID-19: a neglected but critical aspect of SARS-CoV-2 infection

MW Russell, Z Moldoveanu, PL Ogra… - Frontiers in …, 2020 - frontiersin.org
immunity including innate responses. This article proposes that there is a significant role for
mucosal immunity and for … Moreover, it is possible that mucosal immunity can be exploited for …

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

N Smith, P Goncalves, B Charbit, L Grzelak… - Nature …, 2021 - nature.com
immune responses during SARS-CoV-2 infection 4,5,6,7,8,9,15 , we have scant knowledge
concerning how mucosal immunity is … processes, we compared immune responses in paired …

Development of SARS-CoV-2 vaccines: should we focus on mucosal immunity?

L Moreno-Fierros, I García-Silva… - Expert Opinion on …, 2020 - Taylor & Francis
… (including mucosal routes) will also generate important insights for the field. In conclusion,
considering mucosal immunity in the race of developing efficient vaccines against SARS-CoV-…

Mucosal immunity: The missing link in comprehending SARS-CoV-2 infection and transmission

MW Russell, J Mestecky - Frontiers in immunology, 2022 - frontiersin.org
… the response to SARS-CoV-2 infection. We further consider how mucosal immunity might
be … not only to prevent infection and disease but also to suppress transmission of SARS-CoV-2. …

Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination

J Tang, C Zeng, TM Cox, C Li, YM Son, IS Cheon… - Science …, 2022 - science.org
… The goal of the study was to identify the respiratory mucosal immune response after COVID-19
vaccination. We recruited a cohort of unvaccinated healthy individuals (n = 5) and COVID-…

Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

D Lapuente, J Fuchs, J Willar, A Vieira Antão… - Nature …, 2021 - nature.com
… to harness the full potential of mucosal immunity at the entry port of SARS-CoV-2 infections.
… and additionally results in an unmatched mucosal immune response to SARS-CoV-2. Thus, …

Mucosal immunity to SARS-CoV-2: a clinically relevant key to deciphering natural and vaccine-induced defences

C Matuchansky - Clinical Microbiology and …, 2021 - clinicalmicrobiologyandinfection …
mucosal immune responses against SARS-CoV-2 starts with its entry and early replication in
upper airway mucosal … regional immune network, based on an interactive specific mucosal

Longitudinal systemic and mucosal immune responses to SARS-CoV-2 infection

PF Wright, AC Prevost-Reilly… - The Journal of …, 2022 - academic.oup.com
… This overview demonstrates detection of both systemic and mucosal responses to all
components of SARS-CoV-2 S evaluated in infected individuals. Responses above the mean (ie, …

Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines

R Fraser, A Orta-Resendiz, A Mazein… - Trends in molecular …, 2023 - cell.com
… both the efficacy and durability of existing SARS-CoV-2 vaccines, by inducing … SARS-CoV-2
infection and prevention of transmission are heavily dependent on robust mucosal immune

Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination

E Mitsi, MO Diniz, J Reiné, AM Collins… - Nature …, 2023 - nature.com
… In line with others 17,18,32 , our results indicate that following vaccination alone, SARS-CoV-2
immunity in the respiratory mucosa is limited to humoral immunity, with IgG dominating …