Prospects for mucosal vaccine: shutting the door on SARS-CoV-2

R Mudgal, S Nehul, S Tomar - Human vaccines & …, 2020 - Taylor & Francis
… (SARS-CoV and MERS-CoV), mucosal vaccinationmucosal immunity to confer protection
against SARS-CoV-2. This article summarizes the approaches to an effective mucosal vaccine

Mucosal vaccines for SARS-CoV-2: triumph of hope over experience

D Pilapitiya, AK Wheatley, HX Tan - EBioMedicine, 2023 - thelancet.com
… elicitation by parenteral versus mucosal delivery, and the challenges and opportunities
for mucosal vaccine development for SARS-CoV-2. Localised immunity at mucosal surfaces …

Mucosal vaccines—fortifying the frontiers

EC Lavelle, RW Ward - Nature Reviews Immunology, 2022 - nature.com
… new vaccine technologies to be leveraged to facilitate rational mucosal vaccine design for
… including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and for cancer. …

Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report

JM Knisely, LE Buyon, R Mandt, R Farkas… - npj Vaccines, 2023 - nature.com
… During the workshop, researchers and vaccine developers from around … mucosal vaccines
to block SARS-CoV-2 transmission and reviewed the status of SARS-CoV-2 mucosal vaccine

Development of SARS-CoV-2 vaccines: should we focus on mucosal immunity?

L Moreno-Fierros, I García-Silva… - Expert Opinion on …, 2020 - Taylor & Francis
… inducing protective immunity against SARS outbreaks. Moreover, … Among the SARS-CoV-2
experimental vaccines, those … Thus far several vaccine candidates against SARS-CoV-2 are …

Mucosal vaccines, sterilizing immunity, and the future of SARS-CoV-2 virulence

D Focosi, F Maggi, A Casadevall - Viruses, 2022 - mdpi.com
… We review here the pros and cons of each vaccination strategy, the current mucosal
SARS-CoV-2 vaccines under development, and their implications for public health. …

SARS-CoV-2: immunity, challenges with current vaccines, and a novel perspective on mucosal vaccines

R Sunagar, A Singh, S Kumar - Vaccines, 2023 - mdpi.com
… This approach can be adapted for mucosal vaccines against SARS-CoV-2 utilizing a
genetic … studies are needed to develop safe and effective mucosal vaccines against SARS-CoV-2. …

[HTML][HTML] Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

Y Sui, J Li, R Zhang, SK Prabhu, H Andersen… - JCI insight, 2021 - ncbi.nlm.nih.gov
vaccines can protect against respiratory SARS-CoV-2 exposure. In summary, we have
demonstrated that the mucosal vaccine was … systemic vaccines to provide overall better protection. …

Attacking the intruder at the gate: Prospects of mucosal anti SARS-CoV-2 vaccines

K Karczmarzyk, M Kęsik-Brodacka - Pathogens, 2022 - mdpi.com
… that the developed vaccines are not effective … of SARS-CoV-2. Considering this problem, it
is promising to focus on developing a Coronavirus Disease 2019 (COVID-19) mucosal vaccine

A triple-RBD-based mucosal vaccine provides broad protection against SARS-CoV-2 variants of concern

J Yang, MQ Liu, L Liu, X Li, M Xu, H Lin, S Liu… - Cellular & Molecular …, 2022 - nature.com
… -NC plus the mucosal adjuvant KFD (3Ro-NC + KFDi.n) elicits coordinated mucosal IgA and
… KFD is a promising mucosal vaccine candidate for protection against SARS-CoV-2 Omicron …